This article investigates place-making—a process involving appeals to embodiment, materiality, and spatial arrangement—as a means for building communicative relationships between technical scientific communities and lay publics. Drawing from discourses related to the National Historic Chemical Landmark Program’s 89 landmarks, we illustrate how the National Historic Chemical Landmark Program builds different types of relationships with nonexperts via the utilization of place as (a) narrative framing device, (b) proprietor, and (c) gatekeeper. These findings reveal the ways in which specific strategic place-making gestures can support more or less public engagement in the processes of scientific work and outreach.