FEIBA Use in Neonatal Cardiac Surgery: A Risky Business That Needs Further Investigation

Invited Commentary: Achieving Post-Bypass Hemostasis in Young Children: At What Cost?

“…This study by the group at Mayo is but one of a number of studies being published in other journals looking at the efficacy and safety of PCCs in neonates and children following cardiac surgery with bypass. [4][5][6] These studies are most commonly retrospective, observational, performed in a single center with varying doses, indications for, and timing of administration in a small number of patients with varying results. Given the number of uncontrolled variables and small sample sizes, the results of the individual studies are questionable and cannot be generalizable to other center's patients.…”