Feline atopic dermatitis: a retrospective study of 45 cases (2001–2012)

Ravens, Philippa A.; Xu, Bei J.; Vogelnest, Linda

doi:10.1111/vde.12109

Cited by 60 publications

(132 citation statements)

References 17 publications

(54 reference statements)

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“…Affected cats usually present with excessive dark to black waxy to flaky exudate, erythema, with variable otalgia, canal wall hyperplasia, pruritus and odour . Underlying diseases or co‐morbidities include otoacariasis, atopic dermatitis, and feline idiopathic facial dermatitis, although some cats have no identified predisposing diseases …”

Section: Clinical Presentations In Catsmentioning

confidence: 99%

Biology, diagnosis and treatment ofMalasseziadermatitis in dogs and cats Clinical Consensus Guidelines of the World Association for Veterinary Dermatology

Bond

Morris

Guillot

et al. 2020

Veterinary Dermatology

118

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Background -The genus Malassezia is comprised of a group of lipophilic yeasts that have evolved as skin commensals and opportunistic cutaneous pathogens of a variety of mammals and birds.Objectives -The objective of this document is to provide the veterinary community and other interested parties with current information on the ecology, pathophysiology, diagnosis, treatment and prevention of skin diseases associated with Malassezia yeasts in dogs and cats.Methods and material -The authors served as a Guideline Panel (GP) and reviewed the literature available prior to October 2018. The GP prepared a detailed literature review and made recommendations on selected topics. The World Association of Veterinary Dermatology (WAVD) Clinical Consensus Guideline committee provided guidance and oversight for this process. The document was presented at two international meetings of veterinary dermatology societies and one international mycology workshop; it was made available for comment on the WAVD website for a period of six months. Comments were shared with the GP electronically and responses incorporated into the final document.Conclusions and clinical importance -There has been a remarkable expansion of knowledge on Malassezia yeasts and their role in animal disease, particularly since the early 1990's. Malassezia dermatitis in dogs and cats has evolved from a disease of obscurity and controversy on its existence, to now being a routine diagnosis in general veterinary practice. Clinical signs are well recognised and diagnostic approaches are well developed. A range of topical and systemic therapies is known to be effective, especially when predisposing factors are identified and corrected.

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Section: Clinical Presentations In Catsmentioning

confidence: 99%

Biology, diagnosis and treatment ofMalasseziadermatitis in dogs and cats Clinical Consensus Guidelines of the World Association for Veterinary Dermatology

Bond

Morris

Guillot

et al. 2020

Veterinary Dermatology

118

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“…The most common feline allergic diseases are probably confined to the skin. In contrast to dogs, where very good clinical diagnostic criteria for AD exist, cats exhibit a large variety of disparate cutaneous reaction patterns that are attributed, often without proof, to an allergic aetiology . “Feline atopic dermatitis” is a diagnosis of exclusion.…”

Section: Ait In the Catmentioning

confidence: 99%

“…AIT is used commonly as a treatment for presumptive atopic skin disease in cats with success rates similar to those in dogs . Likewise, AIT has been proposed as treatment for feline allergic asthma, but studies to date are limited to experimentally sensitized cats in the laboratory .…”

Section: Ait In the Catmentioning

confidence: 99%

Allergen immunotherapy in people, dogs, cats and horses – differences, similarities and research needs

Mueller¹,

Jensen‐Jarolim

Roth‐Walter

et al. 2018

Allergy

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In human patients with seasonal allergic rhinoconjunctivitis sensitized to grass pollen, the first successful allergen immunotherapy (AIT) was reported in 1911. Today, immunotherapy is an accepted treatment for allergic asthma, allergic rhinitis and hypersensitivities to insect venom. AIT is also used for atopic dermatitis and recently for food allergy. Subcutaneous, epicutaneous, intralymphatic, oral and sublingual protocols of AIT exist. In animals, most data are available in dogs where subcutaneous AIT is an accepted treatment for atopic dermatitis. Initiating a regulatory response and a production of "blocking" IgG antibodies with AIT are similar mechanisms in human beings and dogs with allergic diseases. Although subcutaneous immunotherapy is used for atopic dermatitis in cats, data for its efficacy are sparse. There is some evidence for successful treatment of feline asthma with AIT. In horses, most studies evaluate the effect of AIT on insect hypersensitivity with conflicting results although promising pilot studies have demonstrated the prophylaxis of insect hypersensitivity with recombinant antigens of biting midges (Culicoides spp.). Optimizing AIT using allergoids, peptide immunotherapy, recombinant allergens and new adjuvants with the different administration types of allergen extracts will further improve compliance and efficacy of this proven treatment modality.

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“…Muitos autores reconhecem o CGEF como uma manifestação de alergia, no entanto, salienta-se a importância de investigar outras possíveis etiologias [2,4,10,13,35], como hipersensibilidade alérgica tipo 1 por atopia felina, alergia alimentar, alergia a pulgas, ou outros ectoparasitas [2,[5][6][7]13,15,29,30,35,36]. Ainda, infecções de herpes vírus felino tipo 1 (FHV-1) ocasionalmente estão associadas com dermatites e estomatites ulcerativas [13,17,22].…”

Section: Introductionunclassified

Epidemiologic and Pathologic Aspects of Feline Eosinophilic Granuloma Complex

Ehlers

Slaviero

Vargas

et al. 2019

Acta Scientiae. Vet.

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Background:The feline eosinophilic granuloma complex (FEGC) includes a group of lesions that affect the skin, mucocutaneous junctions, and oral cavity of cats. It comprises three distinct clinical entities: the eosinophilic ulcer (EU), the eosinophilic plaque (EP) and the eosinophilic granuloma (EG). The EU is usually found in the upper lip. Lesions of EP occur most commonly on the abdomen and medial thigh. The EG lesions usually appear on the tongue and hard palate. The aim of this study is to describe the localization and pathological findings of FEGC through a retrospective study and testing by immunohistochemistry if feline herpesvirus type 1 (FHV-1) infection may be associated. Materials, Methods & Results:The records of biopsy specimens from the Department of Veterinary Pathology of the Universidade Federal do Rio Grande do Sul were recovered and cats diagnosed with FEGC were selected since January 2006 to December 2017. General data, such as age, sex, breed and distribution lesions, were analyzed and compiled. The histological slides were reviewed by optical microscopy and the microscopic findings were detailed. Sections of tissue were used in immunohistochemistry to investigate the presence of feline herpesvirus-1 (FHV-1) using anti-FHV-1 antibody. In this study, 30 cats were diagnosed with FEGC. Most part of the cats were mixed breed (27/30), and there were no sex predisposition. The age of the cats ranged from seven months to 13 years old, and the median was three years. The lesion distribution of FEGC was 40% in oral cavity, 33.3% in skin and 26.6% in mucocutaneous junction. Histologically, the main lesion of all distributions was characterized by diffuse dermal/submucosa inflammatory infiltrate composed of eosinophils. Within the inflammation there were large irregular foci of collagen fibers and degranulated and degenerating eosinophil ("flame figures"). Oftentimes these foci were surrounded by macrophages and fewer multinucleated histiocytic giant cells. There were mild to moderate inflammatory infiltrate of mast cells, lymphocytes and plasm cells in dermis and submucosa. Ulceration of epidermis and mucosa were observed in majority of FEGC lesions with inflammatory infiltrate of neutrophils. All cases were negative for FHV-1 in the immunohistochemical evaluation. Discussion: In this study, feline eosinophilic granuloma complex was uncommon, accounting 0.96% of the feline cases diagnosticated in 15 years. Agreeing with the other authors, there was no sex and breed predilection. The median of age were three years old, some authors report higher occurrence in young animals and associated with genetic predisposition. Histologically, the most frequent findings were submucous and dermal inflammatory infiltrate composed primarily of eosinophils associated with areas of "flame figures". Surrounded these areas, there were intense inflammatory infiltrate composed of macrophages, palisading macrophages and fewer multinucleated histiocytic giant cells as previously described by other authors. The ulceration of ...

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Feline atopic dermatitis: a retrospective study of 45 cases (2001–2012)

Abstract: The prevalence of feline AD was higher than previously suggested, and breed predispositions were confirmed. Severe nonseasonal pruritus was most common, with a varied spectrum of lesions affecting a range of body areas.

Cited by 60 publications

References 17 publications

Biology, diagnosis and treatment ofMalasseziadermatitis in dogs and cats Clinical Consensus Guidelines of the World Association for Veterinary Dermatology

Biology, diagnosis and treatment ofMalasseziadermatitis in dogs and cats Clinical Consensus Guidelines of the World Association for Veterinary Dermatology

Allergen immunotherapy in people, dogs, cats and horses – differences, similarities and research needs

Epidemiologic and Pathologic Aspects of Feline Eosinophilic Granuloma Complex

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