Feline Calcium Oxalate Urolithiasis

Bartges, Joseph W.

doi:10.1177/1098612x16660442

Cited by 34 publications

(18 citation statements)

References 55 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Excess mineral control is easier in wet foods for its higher content in fresh meat, avoiding excess of minerals, like calcium, magnesium, and phosphorus, which are more commonly present in meat meals used in dry foods (HAND et al, 2010). This protein-ash content ratio in ingredients is very important, especially when cats are concerned, as higher ash content in foods can predispose cats to uroliths (BARTGES, 2016;LULICH et al, 2016). The lower ash content allied with higher moisture justifies the use of wet foods to help treat, control, and prevent low urinary tract diseases in cats (HAND et al, 2010).…”

Section: Resultsmentioning

confidence: 99%

Nutritional composition and evaluation of different methodologies for fat determination in wet feed for dogs and cats

Urrego

Ernandes

Matheus

et al. 2017

Braz. J. Vet. Res. Anim. Sci.

View full text Add to dashboard Cite

Devido ao aumento do número de cães e gatos domiciliados, a indústria de alimentos para animais de estimação tem expandido a gama de produtos existentes no mercado de pet food. Para obter informações mais relevantes sobre o segmento de alimentos úmidos para cães e gatos, este trabalho determinou a composição nutricional, avaliou as informações declaradas nos rótulos e comparou a composição com as recomendações da Fediaf de proteína e gordura. Também foram comparadas três metodologias diferentes de análise de gordura: extrato etéreo (CFa), extrato etéreo após hidrólise ácida (CFAH) e teor de gordura obtido no analisador Ankom XT15 (ANKOM) para determinar o método mais adequado de avaliação de gordura em alimentos úmidos. Foram avaliadas 25 marcas de alimentos úmidos, 13 para cães e 12 para gatos. As análises de composição centesimal obtidas neste estudo foram comparadas com a informação nutricional declarada nos rótulos e com as necessidades mínimas recomendadas pela Fediaf para cada espécie. Os resultados da composição nutricional, os valores descritos no rótulo e a avaliação dos três métodos para determinação da gordura foram comparados com o emprego do teste t e modelo misto com medidas repetidas nas mesmas amostras, respectivamente (p < 0,05) no programa SAS. Já a avaliação da adequação nutricional de proteína e do teor de gordura foram analisados por cálculos matemáticos de diferença e proporção. Para a maioria dos alimentos avaliados não foi observada diferença entre a composição nutricional dos alimentos úmidos e os valores declarados em rótulo, e houve predominância de produtos que excederam as recomendações mínimas de proteína e gordura da Fediaf para ambas as espécies. Quanto às metodologias de extração de gordura, não foi observada diferença entre os três métodos avaliados (p = 0,68). Concluiu-se que os alimentos úmidos avaliados atendem às informações declaradas pelos fabricantes e também às recomendações nutricionais da Fediaf com base na ingestão energética recomendada. Em relação às metodologias avaliadas para determinação de gordura nestes alimentos, a similaridade entre tais resultados justifica o uso da técnica de maior facilidade ou de menor custo.

show abstract

Section: Resultsmentioning

confidence: 99%

Nutritional composition and evaluation of different methodologies for fat determination in wet feed for dogs and cats

Urrego

Ernandes

Matheus

et al. 2017

Braz. J. Vet. Res. Anim. Sci.

View full text Add to dashboard Cite

show abstract

“…While this hypercalciuria is not necessarily associated with hypercalcemia [42], idiopathic hypercalcemia does occur in cats and has been associated with calcium oxalate urolithiasis [44, 45]. Other potential causes of hypercalciuria may include treatment with loop diuretics or corticosteroids, excess vitamin C or D, and treatment with urinary acidifiers [46], although these are not well described in cats.…”

Section: Epidemiology and Risk Factors For Calcium Oxalate Stone Formmentioning

confidence: 99%

Pathogenesis of calcium oxalate urinary stone disease: species comparison of humans, dogs, and cats

2017

View full text Add to dashboard Cite

Idiopathic calcium oxalate nephrolithiasis is a highly recurrent disease that is increasing in prevalence. Decades of research have not identified effective methods to consistently prevent the formation of nephroliths or induce medical dissolution. Idiopathic calcium oxalate nephroliths form in association with renal papillary subepithelial calcium phosphate deposits called Randall’s plaques (RPs). Rodent models are commonly used to experimentally induce calcium oxalate crystal and stone formation, but a rodent model that conclusively forms RPs has not been identified. Both dogs and cats form calcium oxalate uroliths that can be recurrent, but the etiopathologic mechanisms of stone formation, especially renal pathologic findings, are a relatively unexploited area of study. A large animal model that shares a similar environment to humans, along with a shorter lifespan and thus shorter time to recurrence, might provide an excellent means to study preventative and therapeutic measures, along with enhancing the concepts of the One Health initiative. This review article summarizes and compares important known features of idiopathic calcium oxalate stone disease in humans, dogs, and cats, and emphasizes important knowledge gaps and areas for future study in the quest to discover a naturally occurring animal model of idiopathic calcium oxalate stone disease.

show abstract

“…Urolithiasis in dogs and cats has been much studied in recent years and management of this disorder is evolving, with nutrition being a keystone for the management of these animals (Jeremias et al 2013, Lulich et al 2016, since diet influences urinary pH, and it has a strong influence on certain types of urolith formation (Bartges & Callens 2015, Bartges 2016.…”

Section: Introductionmentioning

confidence: 99%

Effect of calcium sources in the diets of adult cats on urinary parameters and acid-base balance

et al. 2018

View full text Add to dashboard Cite

Calcium is a macroelement that is part of the mineral composition of the diet of companion animals, and is considered a cation of strong alkalizing power, increasing urinary pH. Calcium salts have different solubilities and depending on the anion to which calcium is associated with, it can be more or less absorbed, modifying the pH of the urine. The aim of this study was to evaluate the efficiency of calcium sources on alkalinization of urinary pH, as well as excretion of urinary electrolytes and acid-base balance of adult cats. An extruded diet for cats was selected, and had 160mEq/kg of calcium from the sources of either calcium carbonate (CaCO3) or calcium gluconate (C12H22CaO14) added. In the control treatment there was no addition of calcium sources, resulting in three treatments. Nine adult cats were used, mixed breed, in two experimental periods, with six replicates per treatment. Animal average age was 4±1.3 years old and average weight was 3.96±0.71kg. The cats remained in metabolic cages for an adaptation period of seven days, followed by six days of urine total collection, with volume, density, pH and calcium concentration (g/d) measurements. The acid-base balance was studied by blood gas analysis of venous blood. The two sources of calcium alkalinized the urine (P<0.001). However, calcium gluconate had less alkalinization power compared to the calcium carbonate (P<0.05). Urinary calcium was not affected by treatments, and represented less than 0.5% of calcium intake. The experiment showed that calcium, although an alkaline cation and considered strong influencer of the EB of the diet, cannot be evaluated individually, because depending on its associated anion it may have greater or lesser influence on cats urine pH.

show abstract

Feline Calcium Oxalate Urolithiasis

Cited by 34 publications

References 55 publications

Nutritional composition and evaluation of different methodologies for fat determination in wet feed for dogs and cats

Nutritional composition and evaluation of different methodologies for fat determination in wet feed for dogs and cats

Pathogenesis of calcium oxalate urinary stone disease: species comparison of humans, dogs, and cats

Effect of calcium sources in the diets of adult cats on urinary parameters and acid-base balance

Contact Info

Product

Resources

About