Feline immunodeficiency virus, feline leukaemia virus, Toxoplasma gondii, and intestinal parasitic infections in Taiwanese cats

Lin, Dah-Sheng; Lai, Shiow-Suey; Bowman, Dwight D.; Jacobson, Richard H.; Barr, Margaret C.; Giovengo, Susan L.

doi:10.1016/0007-1935(90)90037-4

Cited by 23 publications

(17 citation statements)

References 10 publications

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“…The prevalence and risk factors associated with FeLV or FIV were determined among domestic cats in peninsular Malaysia. Prevalence of FeLV or FIV in this study was greater than in the United Kingdom, North America, and Taiwan [12][13][14]. The observed differences might be attributed to variation among geographic regions, cat population densities, lifestyles and control policies and practices among different countries.…”

Section: Prevalencecontrasting

confidence: 51%

Prevalence and risk factors of feline leukaemia virus and feline immunodeficiency virus in peninsular Malaysia

et al. 2012

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BackgroundFeline leukaemia virus (FeLV) and feline immunodeficiency virus (FIV) are major causes of morbidity and mortality in domestic and wild felids. Despite the clinical importance of feline retroviruses and the growing interest in cats as pets, information about FeLV and FIV in Malaysia is presently insufficient to properly advise veterinarians and pet owners. A cross-sectional study was carried out from January 2010 to December 2010 to determine the prevalence and risk factors associated with FeLV and FIV among domestic cats in peninsular Malaysia. Plasma samples were harvested from the blood of 368 domestic cats and screened for evidence of FeLV p27 antigen and FIV antibodies, using an immunochromatographic kit. Additionally, data on cat demographics and health were collected using a structured questionnaire, and were evaluated as potential risk factors for FeLV or FIV status.ResultsOf the 368 cats that were evaluated in this study, 12.2% (45/368; 95% CI = 8.88 - 15.58) were positive for FeLV p27 antigen, 31.3%, (115/368; 95% CI = 26.51 - 35.99) were seropositive to FIV antibodies, and 4.3% (16/368; 95% CI = 2.27 - 6.43) had evidence of both viruses. Factors found to significantly increase the risk for FeLV seropositivity include sex, age, behaviour, sickness, and living in a multi-cat household. Seropositive response to FIV was significantly associated with sex, neuter status, age, behaviour, and health status.ConclusionsThe present study indicates that FeLV and FIV are common among domestic cats in peninsular Malaysia, and that factors related to cat demographics and health such as age, sex, behaviour, health status and type of household are important predictors for seropositive status to FeLV or FIV in peninsular Malaysia. High prevalence of FeLV or FIV observed in our study is of concern, in view of the immunosuppressive potentials of the two pathogens. Specific measures for control and prevention such as screening and routine vaccination are needed to ensure that FeLV and FIV are controlled in the cat population of peninsular Malaysia.

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Section: Prevalencecontrasting

confidence: 51%

Prevalence and risk factors of feline leukaemia virus and feline immunodeficiency virus in peninsular Malaysia

et al. 2012

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“…The KELA was developed for the serodiagnosis of a variety of infections (Tsang et al, 1981;Sampson et al, 1983;Mathews et al, 1984), including neosporosis in cattle (Paré et al, 1995;Dubey et al, 1997). Until now, only very few studies describing the use of KELA for detection of T. gondiispecific antibodies in cats (Lin et al, 1990(Lin et al, , 1992, dogs (Lin, 1998) and sheep (Werre et al, 2002) were published, and none of them used recombinant antigens.…”

Section: Discussionmentioning

confidence: 96%

Prevalence of specific IgG-antibodies against Toxoplasma gondii in domestic turkeys determined by kinetic ELISA based on recombinant GRA7 and GRA8

Koethe¹,

Pott²,

Ludewig³

et al. 2011

Veterinary Parasitology

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“…size, 0.45 p.m) plasma from a pool obtained from four cats experimentally infected with FIV. This plasma pool had immunoglobulin G (IgG) kinetics-based enzyme-linked immunosorbent assay (KELISA) values (19,23) (see below) of close to 0 for T. gondii Ag and greater than 0.3 for FIV Ag. By Western blot (immunoblot) analysis, FIV Ags p15, p26, p32, and p45 to p52 were also recognized by this plasma pool (3).…”

Section: Methodsmentioning

confidence: 99%

Immunological changes in cats with concurrent Toxoplasma gondii and feline immunodeficiency virus infections

1992

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To examine the immunological changes in cats concurrently infected with feline immunodeficiency virus (FIV) and Toxoplasma gondii, kittens (four per group) were inoculated with FIV, T. gondii, both agents, or no pathogens. Blood mononuclear cells and plasma were collected weekly for lymphocyte assays and serology. At week 14, spleen and lymph node cells were used for lymphocyte assays; brains and mesenteric lymph nodes were used for isolation of T. gondii. More T. gondii organisms were present in tissues of the dually infected cats than in tissues of cats with toxoplasmosis alone. Two dually infected cats and one cat infected with T. gondii developed chorioretinitis. Spleen, lymph node, and blood mononuclear cells from dually infected cats had the greatest reduction in mitogenic responses. By week 3, cats infected with FIV underwent a decrease in the number of CD4 cells that was not changed by concurrent T. gondii infection; the number of CD8 cells increased only in cats infected with T. gondii alone. For cats infected with T. gondii, the responses of lymphocytes to T. gondii antigen were not affected by FIV infection; the responses to FIV antigen were negligible in all groups. Overall, this study indicates that FIV infection favors T. gondii proliferation. Also, the establishment of toxoplasmosis may enhance FIV-induced immunodeficiency and is likely to cause a more rapid disease progression than that from infection with FIV alone.

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Feline immunodeficiency virus, feline leukaemia virus, Toxoplasma gondii, and intestinal parasitic infections in Taiwanese cats

Cited by 23 publications

References 10 publications

Prevalence and risk factors of feline leukaemia virus and feline immunodeficiency virus in peninsular Malaysia

Prevalence and risk factors of feline leukaemia virus and feline immunodeficiency virus in peninsular Malaysia

Prevalence of specific IgG-antibodies against Toxoplasma gondii in domestic turkeys determined by kinetic ELISA based on recombinant GRA7 and GRA8

Immunological changes in cats with concurrent Toxoplasma gondii and feline immunodeficiency virus infections

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