FEM-Based Compression Fracture Risk Assessment in Osteoporotic Lumbar Vertebra L1

Maknickas, Algirdas; Alekna, Vidmantas; Ardatov, Oleg; Chabarova, Olga; Zabulionis, Darius; Tamulaitienė, Marija; Kačianauskas, Rimantas

doi:10.3390/app9153013

Cited by 13 publications

(12 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, these studies mainly focused on the pedicle screw system's fixation strength rather than quantitatively analyzing the local biomechanical response proposed in the present study. In fact, the analysis of stress distribution and peak/average stress levels are thought to be relevant for fracture risk assessment (Maknickas et al, 2019;Takano et al, 2017;Keyak et al, 1997). Our results, also in agreement with data reported in Sawa et al (2016) for the cortical bone, seem to support the findings reported in Youssef et al (1999), Cho et al (2010), Hussain et al (2009), Mohi Eldin (2014, indicating a medial and caudal trajectory as the most advantageous.…”

Section: Discussionsupporting

confidence: 92%

Effect of pedicle screw angles on the fracture risk of the human vertebra: A patient-specific computational model

Molinari

Falcinelli

Gizzi

et al. 2021

Journal of the Mechanical Behavior of Biomedical Materials

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 92%

Effect of pedicle screw angles on the fracture risk of the human vertebra: A patient-specific computational model

Molinari

Falcinelli

Gizzi

et al. 2021

Journal of the Mechanical Behavior of Biomedical Materials

View full text Add to dashboard Cite

“…In the comparative studies of Kayak et al [ 55 ] and Tellache et al [ 56 ], dealing with the examination of stress- and strain-based failure theories applied to femoral bone fracture prediction, it was stated that the Huber–von Mises–Hencky criterion was robust. This criterion is frequently applied for the trabecular bone failure prediction, for example in [ 57 , 58 ].…”

Section: Discussionmentioning

confidence: 99%

Bone Density Micro-CT Assessment during Embedding of the Innovative Multi-Spiked Connecting Scaffold in Periarticular Bone to Elaborate a Validated Numerical Model for Designing Biomimetic Fixation of Resurfacing Endoprostheses

et al. 2021

View full text Add to dashboard Cite

Our team has been working for some time on designing a new kind of biomimetic fixation of resurfacing endoprostheses, in which the innovative multi-spiked connecting scaffold (MSC-Scaffold) that mimics the natural interface between articular cartilage and periarticular trabecular bone in human joints is the crucial element. This work aimed to develop a numerical model enabling the design of the considered joint replacement implant that would reflect the mechanics of interacting biomaterials. Thus, quantitative micro-CT analysis of density distribution in bone material during the embedding of MSC-Scaffold in periarticular bone was applied. The performed numerical studies and corresponding mechanical tests revealed, under the embedded MSC-Scaffold, the bone material densification affecting its mechanical properties. On the basis of these findings, the built numerical model was modified by applying a simulated insert of densified bone material. This modification led to a strong correlation between the re-simulation and experimental results (FVU = 0.02). The biomimetism of the MSC-Scaffold prototype that provided physiological load transfer from implant to bone was confirmed based on the Huber–von Mises–Hencky (HMH) stress maps obtained with the validated finite element (FE) model of the problem. The micro-CT bone density assessment performed during the embedding of the MSC-Scaffold prototype in periarticular bone provides insight into the mechanical behaviour of the investigated implant-bone system and validates the numerical model that can be used for the design of material and geometric features of a new kind of resurfacing endoprostheses fixation.

show abstract

“…The Mecmesin AFG25 cell-controlled deformation was measured with an accuracy of ±0.01 mm, and the compressive force ranged from 2 to 2,500 N, with an accuracy 100 of ±0.1% and a cross-speed accuracy of ±0.1%. The experiment examined the mechanical qualities of the imprinted 3D model of the lumbar spine using this device ( Maknickas et al , 2019 ). Each vertebra was compressed with 950 N. The selected speed was 1 mm/minute ( Fig.…”

Section: Case Detailsmentioning

confidence: 99%

Empirical case report of the mechanical properties of three spayed canine lumbar vertebrae

Kostenko¹,

Stonkus²,

Šengaut³

et al. 2022

Open Vet J

Self Cite

View full text Add to dashboard Cite

Background: Today, animals, like humans, suffer from spinal illnesses, which are aggravated in old age. Much emphasis is placed on diagnosis and treatment, but little focus is given to the spine's mechanical properties. Degenerative spine diseases are a major problem throughout the world. According to the World Health Organization, osteoporosis is a world-class public problem that reduces bone mass, resulting in bone fracturing and increased risk of bone fracturing. Therefore, the mechanical investigation of vertebrae can provide more information about the development of osteoporosis. Case Description: For our case report, we used spayed mongrel lumbar vertebrae samples obtained from a canine which was about 8 years old and weighed 28 kg. The dog was diagnosed with a mammary tumour, and the dog’s owners decided to euthanise the dog. All consent forms were filled. Conclusions: Mechanical tests were performed on three vertebrae, and a noticeable difference was observed in the first cycle of the first vertebra (L1). Second-order polynomials for displacement and seventh-order polynomials for pressure were proposed for describing the stress–strain relation of the vertebrae under the cyclical loads. Our research protocol has been broken down into several parts. After measuring the area of the loaded surface, the largest area was in the L2 vertebra (176 mm ± 16; 177 mm ± 3 mm), and the smallest was in the L7 vertebra (156 mm ± 4 mm; 151 mm ± 33 mm). The smallest distance was recorded between the first (L1) and seventh (L7) lumbar vertebrae (L1) (15.17 mm ± 0.93 mm), and the largest distance was recorded between the L3 and L4 vertebrae of the lumbar (19.8 mm ± 3.7 mm).

show abstract

FEM-Based Compression Fracture Risk Assessment in Osteoporotic Lumbar Vertebra L1

Cited by 13 publications

References 43 publications

Effect of pedicle screw angles on the fracture risk of the human vertebra: A patient-specific computational model

Effect of pedicle screw angles on the fracture risk of the human vertebra: A patient-specific computational model

Bone Density Micro-CT Assessment during Embedding of the Innovative Multi-Spiked Connecting Scaffold in Periarticular Bone to Elaborate a Validated Numerical Model for Designing Biomimetic Fixation of Resurfacing Endoprostheses

Empirical case report of the mechanical properties of three spayed canine lumbar vertebrae

Contact Info

Product

Resources

About