Female Genital Tract Malignancies during Puberty Uterine and Cervical Malignancies

Abstract

Malignancies of the uterine corpus are extremely rare. Diagnostic and therapeutic procedures should be performed according to oncological principles with individually adapted treatment regimes. Clinical cancer of the cervix is rare in adolescence; the treatment is radical surgery. Preclinical stages, that is, CIN III (severe dysplasia, carcinoma in situ) and microinvasive cancer (stages Ia1, Ia2), are important, also because of their frequency. Diagnosis is based on colposcopy, cytology, direct biopsy, histological examination, and conization. In addition, virology (HPV) and DNA cytometry may become prognostic factors. Treatment consists of conization with an exact histological examination in serial sections as a basis for preserving the uterus. The sarcoma botryoides is localized in the cervix in adolescence, whereas it is in the vagina in infants and children.

Lower Genital Tract Disease in Children and Adolescents—A review

“…91 Sarcoma botryoides, a vaginal lesion in the young child, is more likely to present as a cervical lesion in the adolescent. 92,93 Of interest is Dargent's experience with radical trachelectomy, a uterine sparing procedure for cervical carcinoma. 94 Female children and adolescents can present with a wide variety of lower genital tract conditions unique to these age groups.…”

Partus nach konservativer Therapie eines Rhabdomyosarkoms der Zervix

“…Klinisches Leitsymptom ist die vaginale Blutung. Obwohl Rhabdomyosarkome der Zervix in jedem Lebensalter auftreten können, besteht eine deutliche Häufung in der Adoleszenz [1,12]. Bei diesen jungen Patientinnen ist die Frage der Erhaltung der Fertilität mit in das therapeutische Management einzubeziehen.…”