The role of women in economic development and the global environment is vital for progressing them towards the United Nations sustainable development goal (SDG-5) that emphasized the need to empower women in every walk of life. The study examines women’s autonomy in the sustainable development agenda under China’s open innovation system from 1975 to 2019. The study employed an autoregressive distributed lag (ARDL) model, vector autoregressive (VAR) Granger causality, and innovation accounting matrix to estimate parameters. The existing data are summarized and collated in the context of China to explain as a correlational study. The results show that women’s autonomy moderated with technology spills over to decrease greenhouse gas (GHG) emissions and substantiate the hump-shaped relationship between them. The increased spending on research and development (R&D) activities, patent publications, and renewable energy consumption empowers women to be equipped with the latest sustainable technologies to improve environmental quality. The pollution haven hypothesis verifies a given country, where trade liberalization policies tend to increase polluting industries to set up their plants that engaged in dirty production that exacerbate GHG emissions. The causality estimates confirmed that technological innovations and renewable energy consumption leads to women’s autonomy. In contrast, females’ share in the labor force participation rate leads to an increase in renewable energy consumption. Thus, it is evident that there is a positive role of women in the country’s sustainable development.