Femtosecond laser ablation in aqueous solutions: a novel method to synthesize non-toxic metal colloids with controllable size

Kabashin, Andrei V.; Meunier, Michel

doi:10.1088/1742-6596/59/1/074

Cited by 66 publications

(78 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[27][28][29][30]47 Briefly, an Au disc placed on the bottom of a glass vessel filled with aqueous solution (deionized water or solution of PEG or dextran) is illuminated by focused radiation from a Yb:KGW laser (wavelength 1,025 nm, pulse length 480 fs, energy per pulse 95 μJ, repetition rate 1 kHz), as shown in Figure 1A. The intensity of laser radiation is selected to ablate the Au target, and the Au nanoclusters are released into the liquid ambience, forming a colloidal NP solution.…”

Section: Laser-assisted Synthesis and Characterization Of Au-npsmentioning

confidence: 99%

“…26 When released to the aqueous environment, those nanoclusters coalesce and form a colloidal solution of NPs. Laser ablation in deionized water, without stabilizing ligands and reagents, can lead to extremely stable NP solutions in a nearly monodisperse state, 27,28 while the avoidance of such ligands and reagents promises a better biocompatibility. Such exceptional stability is due to an electrical repulsion effect resulting from a substantial negative charging of NPs produced.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Gold nanoparticles prepared by laser ablation in aqueous biocompatible solutions: assessment of safety and biological identity for nanomedicine applications

Correard¹,

Maximova²,

Estève³

et al. 2014

IJN

View full text Add to dashboard Cite

Due to excellent biocompatibility, chemical stability, and promising optical properties, gold nanoparticles (Au-NPs) are the focus of research and applications in nanomedicine. Au-NPs prepared by laser ablation in aqueous biocompatible solutions present an essentially novel object that is unique in avoiding any residual toxic contaminant. This paper is conceived as the next step in development of laser-ablated Au-NPs for future in vivo applications. The aim of the study was to assess the safety, uptake, and biological behavior of laser-synthesized Au-NPs prepared in water or polymer solutions in human cell lines. Our results showed that laser ablation allows the obtaining of stable and monodisperse Au-NPs in water, polyethylene glycol, and dextran solutions. The three types of Au-NPs were internalized in human cell lines, as shown by transmission electron microscopy. Biocompatibility and safety of Au-NPs were demonstrated by analyzing cell survival and cell morphology. Furthermore, incubation of the three Au-NPs in serum-containing culture medium modified their physicochemical characteristics, such as the size and the charge. The composition of the protein corona adsorbed on Au-NPs was investigated by mass spectrometry. Regarding composition of complement C3 proteins and apolipoproteins, Au-NPs prepared in dextran solution appeared as a promising drug carrier. Altogether, our results revealed the safety of laser-ablated Au-NPs in human cell lines and support their use for theranostic applications.

show abstract

Section: Laser-assisted Synthesis and Characterization Of Au-npsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Gold nanoparticles prepared by laser ablation in aqueous biocompatible solutions: assessment of safety and biological identity for nanomedicine applications

Correard¹,

Maximova²,

Estève³

et al. 2014

IJN

View full text Add to dashboard Cite

show abstract

“…The first protocol implied the involvement of a classical geometry of femtosecond laser ablation from a gold target in liquid ambience. 29,30 Briefly, the gold target (99.99%) was placed at the bottom of a glass vessel filled with 20 mL of highly deionized water (18.2 MΩcm). A 2.3 mm diameter beam of Yb:KGW femtosecond laser (Amplitude Systems [Pessac, France], 1025 nm, 480 fs, 500 µJ, 1-5 kHz) was focused with the help of a 750 mm lens onto the target surface to provide the ablation of material.…”

Section: Synthesis Of Au Nanoparticlesmentioning

confidence: 99%

“…Although the size distribution of gold nanoparticles prepared by conventional "long" (nanosecond) laser ablation in deionized water is typically very broadened, [21][22][23][24][25][26][27][28] it can be much improved by adding reactive surfactants (eg, sodium dodecyl sulfate). 23,24 The employment of femtosecond laser radiation is of particular interest for nanoparticle synthesis, as it cannot only provide superior and controllable size characteristics, 29,30 but can also improve solution stability due to a negative charge of formed nanostructures yielding to electrostatic repulsion effects. 31 Here, the employment of femtosecond fragmentation from preliminarily formed nanoparticles can further enhance advantages of ultrashort laser ablation to produce almost monodispersed gold nanoparticles with exceptional stability of colloidal solution in the absence of any protecting ligand.…”

Section: Introductionmentioning

confidence: 99%

Ultra-pure, water-dispersed Au nanoparticles produced by femtosecond laser ablation and fragmentation

Kubiliūtė¹,

Maximova²,

Lajevardipour³

et al. 2013

IJN

View full text Add to dashboard Cite

Aqueous solutions of ultra-pure gold nanoparticles have been prepared by methods of femtosecond laser ablation from a solid target and fragmentation from already formed colloids. Despite the absence of protecting ligands, the solutions could be (1) fairly stable and poly size-dispersed; or (2) very stable and monodispersed, for the two fabrication modalities, respectively. Fluorescence quenching behavior and its intricacies were revealed by fluorescence lifetime imaging microscopy in rhodamine 6G water solution. We show that surface-enhanced Raman scattering of rhodamine 6G on gold nanoparticles can be detected with high fidelity down to micromolar concentrations using the nanoparticles. Application potential of pure gold nanoparticles with polydispersed and nearly monodispersed size distributions are discussed.

show abstract

“…A variety of nanofluids have been prepared by laser ablation method [21][22][23][24] by ablating solid metals, semiconductors, etc which are submerged in the base fluid (water, lubrication oils, etc). By creating a nanofluid in this way, stable nanofluids resulted without using any property-changing dispersants.…”

Section: Synthesis Of Nanofluidsmentioning

confidence: 99%

Thermal Conductivity of Nanofluids

Singh

2008

DSJ

130

View full text Add to dashboard Cite

Nanofluids are suspensions of nanoparticles in base fluids, a new challenge for thermal sciences provided by nanotechnology. Nanofluids have unique features different from conventional solid-liquid mixtures in which mm or µm sized particles of metals and non-metals are dispersed. Due to their excellent characteristics, nanofluids find wide applications in enhancing heat transfer. Research work on the concept, heat transfer enhancement mechanism, and application of the nanofluids is still in its primary stage. This study provides a review of research in this field with focus on thermal conductivity studies of nanofluids.

show abstract

Femtosecond laser ablation in aqueous solutions: a novel method to synthesize non-toxic metal colloids with controllable size

Cited by 66 publications

References 22 publications

Gold nanoparticles prepared by laser ablation in aqueous biocompatible solutions: assessment of safety and biological identity for nanomedicine applications

Gold nanoparticles prepared by laser ablation in aqueous biocompatible solutions: assessment of safety and biological identity for nanomedicine applications

Ultra-pure, water-dispersed Au nanoparticles produced by femtosecond laser ablation and fragmentation

Thermal Conductivity of Nanofluids

Contact Info

Product

Resources

About