2024
DOI: 10.1002/adhm.202400849
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Femtosecond Laser Maskless Optical Projection Lithography of Cartilage PCM Inspired 3D Protein Matrix to Chondrocyte Phenotype

Teng Li,
Jie Liu,
Min Guo
et al.

Abstract: Hydrogels containing chondrocytes have exhibited excellent potential in regenerating hyaline cartilage. However, chondrocytes are vulnerable to dedifferentiation during in vitro culture, leading to fibrosis and mechanical degradation of newly formed cartilage. We propose to modulate cartilage formation via the developed chondrocyte pericellular matrix (PCM) ‐like scaffolds for the first time, in which the S, M and L‐sized scaffolds were fabricated by femtosecond laser maskless optical projection lithography of… Show more

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