Femur Metastasis: A Rare Metastatic Site in Carcinoma Cervix

Abstract

Background: Cancer cervix is known to spread to distant sites including bones. Long bone metastasis is relatively rare and only handful of cases have been reported. Therefore, bone scan is routinely used in staging of cancer cervix. We report a rare case of cancer cervix with controlled primary and isolated metastasis to femur. Case Report: A 45 year female patient of cancer cervix IIB was treated by chemo-radiotherapy to pelvis and para-aortic region. On follow up, she developed isolated bone lesion in upper 1/3 rd of femur. Femoral involvement was histologically proven squamous cell carcinoma, consistent with the primary pathology. She was treated by surgical resection of metastatic disease with total hip replacement, followed by adjuvant chemotherapy. Presently she is on follow up for 10 months and asymptomatic. Conclusion: Bony metastasis may reduce the survival significantly and therefore early diagnosis and adequate treatment may lead to better quality of life in these patients.

Solitary splenic metastasis in a case of treated cervical cancer: a case report

“…2 Several factors contribute to distant metastases which include advanced stage, endometrial extension and local failure. 5 Malignancies known to metastasize frequently are melanoma, kidney, lung, thyroid cancer, lymphoma, and leukaemia and colon cancer. 8 Distant metastasis from cervix cancer to unusual sites such as the breast, skeletal muscle, duodenum, femur, skin or spleen are extremely rare.…”

“…8 Distant metastasis from cervix cancer to unusual sites such as the breast, skeletal muscle, duodenum, femur, skin or spleen are extremely rare. 2,4,5,8,9 Knowledge of cervical cancer has increased greatly regarding the etiological agent human papillomavirus, pathogenesis and its metastatic pathways.…”