Fentanyl-droperidol neuroleptanalgesia in gastrointestinal endoscopy

Rozen, Paul; Ratan, John; Gilat, Tuvia

doi:10.1016/s0016-5107(77)73619-3

Cited by 14 publications

(3 citation statements)

References 13 publications

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“…Teniendo en cuenta estas evidencias científicas, y considerando los escenarios reales en la práctica endoscópica en España, podemos indicar que la mayoría de los procedimientos bajo sedoanalgesia se llevan a buen término con el control del médico endoscopista y los ayudantes (ATS-DUE). Sin embargo, hay situaciones concretas que aconsejan la consulta y presencia de un especialista en anestesiología y reanimación [28][29][30][31] . Estas situaciones se caracterizan por la necesidad de sedación profunda y por tener asociado al menos uno de los siguientes factores:…”

Section: ¿Es Necesario El Anestesiólogo Para La Sedación En Endoscopias?unclassified

Documento de consenso de la Asociación Española de Gastroenteología sobre sedoanalgesia en la endoscopia digestiva

Simón

Bordas

Campo

et al. 2006

Gastroenterología y Hepatología

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Section: ¿Es Necesario El Anestesiólogo Para La Sedación En Endoscopias?unclassified

Documento de consenso de la Asociación Española de Gastroenteología sobre sedoanalgesia en la endoscopia digestiva

Simón

Bordas

Campo

et al. 2006

Gastroenterología y Hepatología

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“…Because use of adjunctive diphenhydramine is recommended in the difficult-to-sedate patients who fails to achieve adequate sedation with a standard benzodiazepine and opioid combination 3,5 , we pre-defined variables for subgroup analysis that have been suggested to be predictive of difficult-to-sedate patients, including substance abuse (alcohol and drug), opioid use, benzodiazepine use, psychiatric drug use, younger age 5,16,17 , and a composite of substance abuse and opioid, benzodiazepine and psychiatric medication use. Post-hoc multivariable analysis also was undertaken to determine the overall treatment effect of study medication for the primary endpoint when adjusting for these predefined variables.…”

Section: Methodsmentioning

confidence: 99%

Continued midazolam versus diphenhydramine in difficult-to-sedate patients: a randomized double-blind trial

Sachar

Pichetshote

Nandigam

et al. 2018

Gastrointestinal Endoscopy

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“…Trials of ED patients with abdominal pain have shown that haloperidol may improve analgesia and reduce opiate consumption, nausea, and admission rates 34,47–53. Similarly, droperidol has been shown to reduce pain in patients presenting with biliary colic,54 postoperative patients following urologic procedures,55 and during gastrointestinal endoscopy 56,57. Several studies have reported improvements in postoperative pain and reduced opiate consumption with both haloperidol and droperidol 58–60.…”

Section: Introductionmentioning

confidence: 99%

<p>Neuroleptanalgesia for acute abdominal pain: a systematic review</p>

Miller¹,

Khan²,

A³

et al. 2019

JPR

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Background Acute abdominal pain (AAP) comprises up to 10% of all emergency department (ED) visits. Current pain management practice is moving toward multi-modal analgesia regimens that decrease opioid use. Objective This project sought to determine whether, in patients with AAP (population), does administration of butyrophenone antipsychotics (intervention) compared to placebo, usual care, or opiates alone (comparisons) improve analgesia or decrease opiate consumption (outcomes)? Methods A structured search was performed in Cochrane CENTRAL, CINAHL, Database of Abstracts of Reviews of Effects, Directory of Open Access Journals, Embase, IEEE-Xplorer, Latin American and Caribbean Health Sciences Literature, Magiran, PubMed, Scientific Information Database, Scopus, TÜBİTAK ULAKBİM, and Web of Science. Clinical trial registries ( ClinicalTrials.gov , World Health Organization International Clinical Trials Registry Platform, and Australian New Zealand Clinical Trials Registry), relevant bibliographies, and conference proceedings were also searched. Searches were not limited by date, language, or publication status. Studies eligible for inclusion were prospective randomized clinical trials enrolling patients (age ≥18 years) with AAP treated in acute care environments (ED, intensive care unit, postoperative). The butyrophenone must have been administered either intravenously or intra-muscularly. Comparison groups included placebo, opiate only, corticosteroids, non-steroidal anti-inflammatory drugs, or acetaminophen. Results We identified 7,217 references. Six studies met inclusion criteria. One study assessed ED patients with AAP associated with gastroparesis, whereas five studies assessed patients with postoperative AAP: abdominal hysterectomy (n=4), sleeve gastrectomy (n=1). Three of four studies found improvements in pain intensity with butyrophenone use. Three of five studies reported no change in postoperative opiate consumption, while two reported a decrease. One ED study reported no change in patient satisfaction, while one postoperative study reported improved satisfaction scores. Both extrapyramidal side effects (n=3) and sedation (n=3) were reported as unchanged. Conclusion Based on available evidence, we cannot draw a conclusion on the efficacy or benefit of neuroleptanalgesia in the management of patients with AAP. However, preliminary data suggest that it may improve analgesia and decrease opiate consumption.

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Fentanyl-droperidol neuroleptanalgesia in gastrointestinal endoscopy

Cited by 14 publications

References 13 publications

Documento de consenso de la Asociación Española de Gastroenteología sobre sedoanalgesia en la endoscopia digestiva

Documento de consenso de la Asociación Española de Gastroenteología sobre sedoanalgesia en la endoscopia digestiva

Continued midazolam versus diphenhydramine in difficult-to-sedate patients: a randomized double-blind trial

<p>Neuroleptanalgesia for acute abdominal pain: a systematic review</p>

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