Fenugreek Extract Supplementation Has No Effect On The Hormonal Profile Of Resistance-trained Males

Plant-based nutrients have been studied for their potential impact on testosterone production in men. We investigated the influence of a novel passion flower extract on free testosterone in healthy men. In part one of this study, 18 younger men (35.9 ± 1.6 years) were assigned to consume placebo tablets or tablets containing a passion flower extract, in a random order, double-blind, cross-over design. The treatment period for each condition was 15 days, with a two-week washout period between conditions. Blood and saliva were collected both in the morning and the evening on days 1, 8, and 15-both before and one hour following ingestion of the assigned condition. In part two of this study, seven older men (55.9 ± 2.7 years) were assigned to consume the passion flower extract or placebo tablets in a random order, double-blind, cross-over design. The treatment period was the same as for part one and but only saliva was collected in the morning on days 1, 3, 8, and 15. All subjects completed a questionnaire on the morning of each test day to determine their subjective feelings associated with the condition treatment. Passion flower extract did not appear to influence free testosterone or subjective feelings in younger men. However, free salivary testosterone was increased an average of 13% in older men. In addition, an increase of 17% was noted from day 1 to day 15 for perceived energy level, while an increase of 9% was noted for libido when older men used the extract. A novel passion flower extract does not influence testosterone concentrations or subjective feelings in younger men but may have an influence on these outcomes in selected older men. It is possible that the treatment may be more effective when delivered to those with low baseline testosterone values.

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Increasing Circulating Testosterone: Impact of Herbal Dietary Supplements

Gunnels¹

2014

J Plant Biochem Physiol

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Low circulating testosterone levels can present numerous problems related to the overall health and well-being of individuals, men in particular. This finding is well-documented in the literature and low testosterone appears more prevalent in older men, in particular those who are physically inactive and who present with elevated levels of body fat. Multiple botanical (herbal) products have been claimed to elevate circulating testosterone in men; however, data pertaining to the use of such herbal preparations obtained from human clinical trials are limited. This review examines the research to date pertaining to the use of herbal ingredients with regards to their ability to elevate blood testosterone levels. A collective summary of the findings indicate that certain herbal supplements may actually yield an increase in testosterone (e.g., Longjack root), while most others have little to no evidence in support of their use in human subjects. Additional, well-controlled clinical trials are needed to generate data relative to the use of herbal dietary supplements to increase circulating testosterone. Testosterone is generally measured as either "free" (unbound) or "total" (unbound and chemically bound). Men who have a morning serum testosterone level < 300 ng/dL are considered to be "low" and may be a candidate for testosterone replacement therapy-which has become more common in recent years due to the increased diagnosis of andropause [55]. Insufficient levels of testosterone due to either impaired production or uptake can present serious health consequences due to the wide array of applications of testosterone within the human body. Areas including skeletal muscle health, muscular strength, and overall well-being/vitality seem to be significantly affected by testosterone status. Increasing Circulating Testosterone: Impact of Herbal Dietary SupplementsTrintThe role of testosterone in muscle growth has been investigated extensively in both humans and animals [56][57][58][59][60][61][62]. One study in men concluded that the testosterone-induced increase in muscle volume is due to muscle fiber hypertrophy [63]. A follow-up study conducted a year later noted muscle hypertrophy in men over a period of 20 weeks of treatment with a gonadotropin-releasing hormone agonist and a 125-, 300-, or 600-mg weekly dose of testosterone enanthate. The main findings from this study indicated that testosterone administration was associated with a significant increase in myonuclear number in men receiving the 300-and 600-mg doses.Muscular strength is another important factor that has been shown to be affected by testosterone levels in the body [56,61,62,[64][65][66]. A recent investigation utilized 267 men with stages 2-4 of Chronic Kidney Disease to assess the impact of testosterone level on a variety of variables [64]. This study found that testosterone was significantly and independently associated with handgrip strength, muscle mass, and nutritional status as the disease progressed. Another study explored short-term testoste...

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Fenugreek Extract Supplementation Has No Effect On The Hormonal Profile Of Resistance-trained Males

Cited by 3 publications

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Ergogenic properties, safety evaluation and regulations of selected ingredients in testosterone booster dietary supplements

Ergogenic properties, safety evaluation and regulations of selected ingredients in testosterone booster dietary supplements

The influence of a passion flower extract on free testosterone in healthy men: a two part investigation involving younger and older men

Increasing Circulating Testosterone: Impact of Herbal Dietary Supplements

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