2017
DOI: 10.1111/jfbc.12442
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Fermentation of soybean hull byMonascus pilosusand elucidation of its related molecular mechanism involved in the inhibition of lipid accumulation. An in sílico and in vitro approach

Abstract: Soybean fermentation had been done over the years in order to increase its nutritional value. In order to that, our present study was focused on the fermentation of soybean hull (SH) by Monascus pilosus KCCM 60084 to enhance the secondary metabolite monacolin K and produce isoflavones such as daidzein and genistein (phytoestrogens). These isoflavones have effect on reducing cholesterol level, anticancer, and anti‐osteophorosis. Furthermore, the anti‐adipogenesis effect of fermented soybean hull (FSH) and nonfe… Show more

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Cited by 7 publications
(5 citation statements)
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“…In addition, higher levels of phenolics, flavonoids, and biotransformed substances were identified. The fermentation of other soy by-products, such as meal, whey, and hull, has demonstrated vast potential for enhancing the bioactivity of the final products [165][166][167][168][169][170][171].…”
Section: Bioactive Compounds In Industrial By-products From Soybean Processing-an Overview and Trendsmentioning
confidence: 99%
“…In addition, higher levels of phenolics, flavonoids, and biotransformed substances were identified. The fermentation of other soy by-products, such as meal, whey, and hull, has demonstrated vast potential for enhancing the bioactivity of the final products [165][166][167][168][169][170][171].…”
Section: Bioactive Compounds In Industrial By-products From Soybean Processing-an Overview and Trendsmentioning
confidence: 99%
“…Previous studies show that fermented soybean hull, Monascus pilosus -fermented black soybean extracts, and Lactobacillus paracasei subsp. paracasei NTU101-fermented tea can reduce the proliferation of 3T3-L1 cells and inhibit lipid accumulation in the 3T3-L1 cell [ 29 , 30 , 31 ]. These results show that fermented plants administration can reduce the proliferation of 3T3-L1 cells and inhibit lipid accumulation.…”
Section: Discussionmentioning
confidence: 99%
“…ruber [ 11 , 12 ] and M . pilosus [ 13 15 ] have a strong capacity to produce monacolin K. Nevertheless, M . purpureus is the most predominant microorganisms for the efficient production of MPs because of its high efficiency to produce pigments [ 16 18 ].…”
Section: Introductionmentioning
confidence: 99%