Fermentative Bioprocesses for Detoxification of Agri-Food Wastes for Production of Bioactive Compounds

Bioengineered Nanospores Selectively Blocking LC3-Associated Phagocytosis in Tumor-Associated Macrophages Potentiate Antitumor Immunity

“…14,18,24 Nonspecific interference (especially in tumor cells), however, could potentially present the risk of promoting tumor growth and treatment resistance through the canonical autophagy pathway, 25,26 which presented the necessity for TAM-exclusive Rubicon knockdown. Rhizopus oryzae, an airborne filamentous fungus widely used in the food industry, 27 exerts exclusive specificity to macrophages with a smaller phagocytosis ratio in other types of cells. 28 Of note, an in vivo study found that over 80% of R. oryzae conidia were colocalized in macrophages after infection.…”