Fermentative Production of Building Blocks for Chemical Synthesis of Polyesters

Abstract

Introduction Historical Outline Dicarboxylic Acids Succinic Acid Adipic Acid Diols 1,2‐Propanediol 1,3‐Propanediol 1,4‐Butanediol Hydroxy Acids Lactic Acid Lactones and Other Cyclic Esters Outlook and Perspectives Acknowledgements Patents

Biosynthesis of the Nylon 12 Monomer, ω‐Aminododecanoic Acid with Novel CYP153A, AlkJ, and ω‐TA Enzymes

“…[5,6] In fact, the hazards associated with chemical manufacturing and increased concerns about process safety open up a new window for alternative biocatalytic synthesis. [7] To date, the microbial host system is considered the most appropriate means for biotechnological production of polymer building blocks for Nylons [8][9][10] or polyesters. [11,12] Furthermore, it has been reported that omega amino dodecanoic acid (ω-AmDDA) or 12 amino dodecanoic acid methyl ester (ADAME) are convenient monomers for Nylon 12 biosynthesis.…”

Fermentative Herstellung von Bernsteinsäure mitBasfia succiniciproducensDD1 in Serumflaschen

“…Marktwertschätzungen für aus Bernsteinsäure hergestellte Produkte belaufen sich auf über 400 Millionen US-Dollar pro Jahr [2]. Momentan wird der Jahresumsatz der Bernsteinsäure, größtenteils petrochemischen Ursprungs, auf circa 15 000 Tonnen geschätzt [3]. Bei einem kostengünstigeren Produkt, vornehmlich auf Basis nachwachsender Rohstoffe, könnte dieses Marktpotential zukünftig ansteigen.…”

Carbohydrate‐based Product Lines: The Key Sugars of Biomass: Availability, Present Non‐Food Uses and Potential Future Development Lines

“…Each of these are considered to have high "building block potential", either as monomers for the production of novel polyesters and polyamides [112] or as a starting material for a variety of commodity chemicals, currently produced petrochemically. Accordingly, these five carboxylic acids are to become economically viable products if low-cost fermentation routes can be developed and implemented on an industrial level.…”