Fermentative production of butanol—the industrial perspective

Green, Edward M.

doi:10.1016/j.copbio.2011.02.004

Cited by 647 publications

(352 citation statements)

References 48 publications

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“…However, substrate cost remains a major factor influencing the economic viability of fermentative butanol production, accounting for up to 50% of the production cost (Green, 2011). Therefore, transition toward cheaper (non-edible) feedstocks offers the biggest opportunity for cost reduction and improved sustainability (Guan et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

Simultaneous saccharification and fermentation of hemicellulose to butanol by a non-sporulating Clostridium species

2016

Bioresource Technology

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h i g h l i g h t sSimultaneous saccharification and fermentation of xylan to butanol by new strain MF28. Simultaneous fermentation of glucose and xylose to produce 11.9 g/L butanol. High yields of butanol on xylan and xylooligosaccharide were obtained. No acetone/ethanol byproducts were formed in converting lignocellulose to butanol. Non-sporulating strain MF28 is capable of continuous industrial-scale fermentation. a r t i c l e i n f o t r a c tProduction of lignocellulosic butanol has drawn increasing attention. However, currently few microorganisms can produce biofuels, particularly butanol, from lignocellulosic biomass via simultaneous saccharification and fermentation. Here we report discovery of a wild-type, mesophilic Clostridium sp. strain MF28 that ferments xylan to produce butanol (up to 3.2 g/L) without the addition of saccharolytic enzymes and without any chemical pretreatments. Application of selective pressure from 2-deoxy-Dglucose facilitated isolation of strain MF28, which exhibits inactivation of genes (gid and ccp genes) responsible for carbon catabolite repression, thus allowing strain MF28 to simultaneously ferment a combination of glucose (30 g/L), xylose (15 g/L), and arabinose (15 g/L) to produce 11.9 g/L of butanol. Strain MF28 possesses several unique features: (i) non-sporulating, (ii) no acetone/ethanol, (iii) complete hemicellulose-binding enzymatic domain, and (iv) absence of carbon catabolite repression. These unique characteristics demonstrate the industrial potential of strain MF28 for cost-effective biofuel generation from lignocellulosic biomass.

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Section: Introductionmentioning

confidence: 99%

Simultaneous saccharification and fermentation of hemicellulose to butanol by a non-sporulating Clostridium species

2016

Bioresource Technology

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“…Butanol is the preferred solvent since it has the highest price. In recent years, with the successful application of the ABE fermentation technology to lignocellulose feedstocks, many countries have established large-scale ABE fermentation plants (Green, 2011;Harvey and Meylemans, 2011).…”

Section: Introductionmentioning

confidence: 99%

Synthesis of renewable diesel with the 2-methylfuran, butanal and acetone derived from lignocellulose

Yang

et al. 2013

Bioresource Technology

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“…The copy number of commonly used plasmids in C. acetobutylicum is around 7-20 copies per cell, which seem to be suitable for metabolic engineering purposes [23]. Significant advances for C. acetobutylicum have been made to methods for gene integration [24]. Superior performance has also been demonstrated from genetically engineered derivatives of C. acetobutylicum ATCC 824 [25,26].…”

Section: Metabolic Engineering Of Mesophilic Clostridiamentioning

confidence: 99%

Lignocellulosic Biomass Utilization Toward Biorefinery Using Meshophilic Clostridial Species

Tamaru¹,

López-Contreras²

2013

Cellulose - Biomass Conversion

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Fermentative production of butanol—the industrial perspective

Cited by 647 publications

References 48 publications

Simultaneous saccharification and fermentation of hemicellulose to butanol by a non-sporulating Clostridium species

Simultaneous saccharification and fermentation of hemicellulose to butanol by a non-sporulating Clostridium species

Synthesis of renewable diesel with the 2-methylfuran, butanal and acetone derived from lignocellulose

Lignocellulosic Biomass Utilization Toward Biorefinery Using Meshophilic Clostridial Species

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