Fermentative Production ofl-Leucine with Auxotrophic Mutants ofCorynebaeterium glutamicum

Regulatory Properties of Prephenate Dehydrogenase and Prephenate Dehydratase fromCorynebacterium glutamicum

“…Therefore, the stimulation may be of secondary physiological significance other than the primary effect of the end product. Araki et al 26 ) reported that a phenylalanine auxotroph of C. glutamicum KY 10233 which lacks prephenate dehydratase activity produced a large amount of L-Ieucine. Their finding suggests a certain correlation between prephenate dehydratase activity and L-Ieucine biosynthesis in C. glutamicum.…”