We study the zero-dimensional reduced model of D = 6 pure super Yang-Mills theory and argue that the large N limit describes the (2, 0) Little String Theory. The one-loop effective action shows that the force exerted between two diagonal blocks of matrices behaves as 1/r 4 , implying a six-dimensional spacetime. We also observe that it is due to non-gravitational interactions. We construct wave functions and vertex operators which realize the D = 6, (2, 0) tensor representation. We also comment on other "little" analogues of the IIB matrix model and Matrix Theory with less supercharges.