Ferret oncology: diseases, diagnostics, and therapeutics

Antinoff, Natalie; Hahn, Kevin A.

doi:10.1016/j.cvex.2004.05.001

Cited by 59 publications

(77 citation statements)

References 59 publications

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“…The prevalence of lymphoma in ferrets ranges from 11.9% to 29.2%. 2,3 Lymphoma in ferrets has been classified into multicentric, gastrointestinal, mediastinal, cutaneous, and extranodal forms according to the site of origin, with no particular age association. 13 Several variants of lymphoma exist in ferrets.…”

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confidence: 99%

Malignant B-Cell Lymphoma with Mott Cell Differentiation in a Ferret (Mustela Putorius Furo)

et al. 2010

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Abstract. A 3.5-year-old, male, neutered ferret (Mustela putorius furo) was presented with a 3-day history of lethargy and anorexia. Splenic aspirates revealed high numbers of intermediate-sized lymphocytes and Mott cells interpreted as lymphoma with Mott cells. The ferret was euthanized because of a poor clinical prognosis. Postmortem examination revealed markedly enlarged spleen and lymph nodes, with multifocal white nodules in the liver parenchyma. Histologically, the spleen had multifocal large nodules composed of neoplastic lymphocytes with frequent Mott cells. Similar neoplastic cells were present in the sections of liver, lymph nodes, and bone marrow. These cells were cluster of differentiation (CD)3-negative, CD79a-positive, and lambda light-chain-positive. Electron microscopy revealed that the cytoplasm of the neoplastic Mott cells had increased, disorganized, dilated, rough endoplasmic reticulum containing electron-dense immunoglobulin. On the basis of cytologic, histopathologic, immunohistochemical, and electron microscopic findings, a malignant B-cell lymphoma with Mott cell differentiation was diagnosed.

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Malignant B-Cell Lymphoma with Mott Cell Differentiation in a Ferret (Mustela Putorius Furo)

et al. 2010

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“…Hence, the early literature suggested that the incidence of neoplasms in ferrets was low [2,5]. However, increased numbers of neoplasms have been reported since the 1990s [1,2,[11][12][13]20] due to the increased population of ferrets as pets and laboratory animals in North America. Currently, there is a large number of reports concerning ferret neoplasms, including epidemiological data, and the fact that neoplasms are much more common in this species than previously indicated has been established.…”

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Neoplasitic Diseases in Ferrets in Japan: A Questionnaire Study for 2000 to 2005

et al. 2009

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ABSTRACT. The objective of this study was to collect epidemiological data on neoplasms in pet ferrets in Japan. A questionnaire to collect information was made available to Japanese veterinary practitioners through the web site of the Japanese Society of Exotic Pet Medicine. Completed questionnaires were returned from 29 practices, and 945 neoplasms met the criteria for inclusion in the study. Neoplasms were found in every organ system except the respiratory system; the endocrine (418; 44.2%), integumentary (196; 20.7%) and hemolymphatic (184; 19.5%) systems were most commonly affected. The most common tumor types were pancreatic islet cell tumor (211: 22.3%), adrenal gland tumor (207; 21.9%) and lymphoma (152; 16.1%). The age of the affected ferrets ranged from less than 3 months to more than 7 years of age. Tumor incidence was highest in ferrets between 4 and 6 years of age. No sex predilection was found.

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“…Some are pruritic, and oral or topical antihistamines can be used to obtain temporary relief. Surgical excision ( Figure 24.7) is generally curative, and premedication with antihistamines or wide surgical margins are not required (Antinoff and Hahn, 2004).…”

Section: Hyperadrenocorticismmentioning

confidence: 99%

“…This is of interest as, until this study, vaccination had not previously been associated with oncogenesis in non-feline species. Wide and deep surgical excision, possibly followed by local radiation, is indicated (Antinoff and Hahn, 2004).…”

Section: Vaccination Site Fibrosarcomasmentioning

confidence: 99%

Ferrets: dermatoses

Meredith¹

2009

BSAVA Manual of Rodents and Ferrets

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Ferret oncology: diseases, diagnostics, and therapeutics

Cited by 59 publications

References 59 publications

Malignant B-Cell Lymphoma with Mott Cell Differentiation in a Ferret (Mustela Putorius Furo)

Malignant B-Cell Lymphoma with Mott Cell Differentiation in a Ferret (Mustela Putorius Furo)

Neoplasitic Diseases in Ferrets in Japan: A Questionnaire Study for 2000 to 2005

Ferrets: dermatoses

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