2024
DOI: 10.33380/2305-2066-2024-13-2-1786
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Ferroptosis inducers – erastin and analogues (review)

E. V. Sanarova,
A. V. Lantsova,
L. L. Nikolaeva
et al.

Abstract: Introduction. Improving the efficacy of chemotherapy is a non-trivial task of modern oncology. Its successful solution requires knowledge in many fields, including physiology, pathology, clinical oncology, pharmacology and others. The search for small molecules that selectively kill tumor cells led to the accidental discovery of erastin.Text. Erastin is a unique molecule that has a quinazoline fragment in its structure. Not so long ago it became known that the antitumour effect of this compound is due to the i… Show more

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