Fertility after abdominal myomectomy

Abstract

This study aimed to evaluate the morbidity and pregnancy outcome of myomectomy in infertile women with uterine fibroids. This was a cross-sectional study. Records were reviewed for 100 consecutive women in the Rotunda Hospital who underwent myomectomy in the years 1995-1996. A questionnaire regarding subsequent fertility was sent. The study was carried out in the infertility unit at the Rotunda Hospital, Dublin, Ireland. Seventy-five women responded. Multiple myomectomy was performed in 52 (70%). Mean fibroid size was 6.8 cm (range 2-14.5 cm). Nine women (12%) developed complications; five had menstrual problems, two had wound discomfort and two had abdominal discomfort. Twenty-five women (33%) became pregnant. Seven (28%) were IVF pregnancies. Overall six (24%) miscarried. In 19 of 25, pregnancy occurred where fibroids were the only identifiable cause of infertility. We conclude that abdominal myomectomy is associated with a favourable outcome in infertile women particularly if no other confounding variable is present.

Uncomplicated term vaginal delivery following magnetic resonance-guided focused ultrasound surgery for uterine fibroids

“…Despite myomectomy being the gold standard, few studies agree on the actual increase in pregnancy rates following surgery, this being described as anything from 44%-81%; however, all report a fall in the rate of pregnancy loss [6-9]. …”

Oral Contraceptives after Myomectomy: A Short Term Trial

“…Myomectomy is associated with a favourable outcome in infertile women, particularly if no other complication variable is present [16]. The location of the myomata may play an important role in determining infertility.…”