Fertility after ectopic pregnancy in a district hospital in Cameroon

Nguefack‐Tsague, Georges; Ateudjeu, Jerôme; Che, Gilbert A.; Mboudou, Emile Télesphore

doi:10.1016/j.ijgo.2015.02.027

Cited by 2 publications

(1 citation statement)

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“…Several studies had evaluated fertility outcomes subsequent to medical and surgical treatment for ectopic pregnancy patients, with a cumulative incidence of intra uterine pregnancy up to 60% [2] [4], but none in our settings evaluates outcomes of fertility after medical treatment [5]. We therefore sought to determine the outcomes of subsequent spontaneous fertility after medical treatment of patients with MTX in patients with ectopic pregnancy at two university hospitals in the city of Yaounde.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Spontaneous Fertility after Medical Treatment of Tubal Ectopic Pregnancy in Two Hospitals in the City of Yaounde

Cyrille,

Hilary,

Robert

et al. 2024

OJOG

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Background: Ectopic pregnancy is a major cause of maternal morbidity and mortality, estimated to occur in 1% -2% of pregnancies worldwide. This condition also has an adverse effect on the fertility prospects of women who experience it. Objective: To determine the outcomes of subsequent spontaneous fertility after medical treatment of patients with methotrexate (MTX) in patients with ectopic pregnancy at two university teaching hospitals of Yaounde. Methodology: We carried out a cross-sectional study with retrospective data collection in two university teaching hospitals of Yaounde during a six years period from 1 st January 2015 to 31 st May 2021. Seventy records of patients who had medical treatment for ectopic pregnancy were included in this study. Statistical analysis was performed using SPSS. 23. The Chi-2 statistical test was used to compare qualitative variables. Binary logistic regression method was performed to identify independent risk factors associated with infertility after medical treatment of tubal ectopic pregnancy (TEP). The significance level was set at 0.05. Results: The mean age in our study population was 27.8 ± 3.8 years. According to the past medical history, 52.9% had a pelvic inflammatory disease (PID) and the most frequently germ found was C. trachomatis (47.1%). Almost 15% of our study population had previous surgery for EP. The median Fernandez score was 11 with a minimum score of 4 and a maximum score of 13. The route of administration of methotrexate was intramuscular in all our patients, and the single-dose protocol was used most frequently (58.6%). After medical treatment of the EP, we found a spontaneous conception rate of 58.6%. After multivariate analysis, we were unable to confirm that there was an association between a history of sexually transmitted infections (STIs) and fertility prognosis. Conclusion: The spontaneous fertility rate after medical management of EP was 58.6%, of which 73.

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Section: Introductionmentioning

confidence: 99%