Fertility Preservation for Pediatric Patients: Current State and Future Possibilities

Johnson, Emilie K.; Finlayson, Courtney; Rowell, Erin E.; Gosiengfiao, Yasmin; Pavone, Mary Ellen; Lockart, Barbara; Orwig, Kyle E.; Brannigan, Robert E.; Woodruff, Teresa K.

doi:10.1016/j.juro.2016.09.159

Cited by 86 publications

(97 citation statements)

References 49 publications

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“…Impaired fertility is an especially challenging late effect that affects many cancer survivors. Male survivors of cancer therapy experience a 50% decrease in fertility compared with siblings, and infertility in female survivors ranges from 16% to 40% . Fertility preservation, including sperm banking and oocyte cryopreservation, poses several challenges for AYAs.…”

Section: Survivorshipmentioning

confidence: 99%

Ethical issues in the care of adolescent and young adult oncology patients

Sisk

Canavera

Sharma

et al. 2019

Pediatric Blood & Cancer

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The diagnosis and treatment of cancer leads to short‐term and long‐term challenges for every patient. This is especially true for adolescents and young adults (AYAs) with cancer who strive to gain independence, autonomy, confidence, and social status while developing into adulthood. In this article, we review prominent ethical issues in AYA oncology that are related to autonomy, shared decision‐making, care refusal or abandonment, end‐of‐life care, truth telling, and fertility preservation. Clinicians should recognize that AYA patients develop at their own pace; the onus lies with clinicians to determine the patient's interests, values, maturity, and desire to participate in decision‐making.

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Section: Survivorshipmentioning

confidence: 99%

Ethical issues in the care of adolescent and young adult oncology patients

Sisk

Canavera

Sharma

et al. 2019

Pediatric Blood & Cancer

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“…55 Consultation with a medical ethicist or their inclusion on the fertility team often is very helpful. These include the right of parental decision making, the child's decisional capacity and right to assent, and what to do if these are at odds.…”

Section: Testicular Tissue Cryopreservationmentioning

confidence: 99%

“…55 Several states now have introduced bills that would mandate coverage for FP procedures for those patients facing potential infertility as a result of medical treatment. Patients who may have insurance coverage for fertility treatments often are unable to use their benefits because they fail to meet the current definitions of "infertility" that rely on 6 to 12 months of attempted conception without pregnancy.…”

Section: Testicular Tissue Cryopreservationmentioning

confidence: 99%

Fertility preservation options in pediatric and adolescent patients with cancer

Burns

Hoefgen

Strine

et al. 2018

Cancer

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The incidence of childhood cancer has steadily increased since the 1950s, with approximately 16,000 children diagnosed each year. However, with the advent of more effective multimodal therapies, childhood cancer survival rates have continued to improve over the past 40 years, with >80% of patients now surviving into adulthood. Fertility preservation (FP) has become an important quality-of-life issue for many survivors of childhood cancer. As a result, the therapeutic options have become less gonadotoxic over time and more patients are being offered FP options. This review examines the indications for consultation, male and female FP options both in the prepubertal patient and adolescent patient, and the unique ethical issues surrounding FP in this vulnerable population. Cancer 2018;124:1867-76. © 2018 American Cancer Society.

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“…Shouldn't the ability to reproduce be a right shared by all? In reality, assisted reproductive technology and fertility preservation are often costly and not covered by insurance, and thus unavailable to many people (78). Should every child have the right to be informed about their fertility potential?…”

Section: Ethical Considerationsmentioning

confidence: 99%

Fertility counseling and preservation: considerations for the pediatric endocrinologist

Saraf

Nahata

2017

Transl. Pediatr

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Infertility is a distressing consequence of numerous pediatric medical conditions and treatments.The field of pediatric fertility preservation has expanded rapidly over the past decade, and clinical guidelines emphasize the importance of discussing infertility risk and fertility preservation options with patients and families in a timely manner. Understanding the various mechanisms and presentations of fertility issues across diagnoses is imperative to provide counseling to patients and families, and identify individuals who may benefit from fertility preservation. The goals of this manuscript are to outline current fertility preservation options in pediatrics, review populations at-risk for infertility that are seen in pediatric endocrinology, and discuss other important issues related to fertility preservation including ethical considerations.

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Fertility Preservation for Pediatric Patients: Current State and Future Possibilities

Cited by 86 publications

References 49 publications

Ethical issues in the care of adolescent and young adult oncology patients

Ethical issues in the care of adolescent and young adult oncology patients

Fertility preservation options in pediatric and adolescent patients with cancer

Fertility counseling and preservation: considerations for the pediatric endocrinologist

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