Fetal and maternal energy metabolism during labor in relation to the available caloric substrate

Scheepers, Hubertina C.J.; Jong, P.A. de; Essed, G.G.M.; Kanhai, H. H. H.

doi:10.1515/jpm.2001.064

Cited by 27 publications

(28 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This is a novel finding and several explanations can be offered: labor imposes metabolic challenge not only on the parturient woman, but also on the fetus. Glucose, the most important fuel for the fetus [10,93], is subject to dynamic metabolic change during the course of labor. Indeed, parturition is associated with an increased fetal blood glucose [86,87].…”

Section: The Presence Of Spontaneous Labor At Term Is Associated Withmentioning

confidence: 99%

“…Indeed, parturition is associated with an increased fetal blood glucose [86,87]. Moreover, umbilical vein concentrations of glucose are lower [36] and those of lactate are higher [93] than in the umbilical artery, suggesting enhanced fetal consumption of glucose during labor. Of note, umbilical cord blood concentrations of glucose, insulin and cortisol are higher in neonates born after spontaneous labor than in neonates born by cesarean delivery in the absence of labor [41], further supporting the notion that labor is an energy consuming state for the fetus.…”

Section: The Presence Of Spontaneous Labor At Term Is Associated Withmentioning

confidence: 99%

“…The conventional view is that labor and delivery can be viewed as a moderate exercise [6,30] and that similar, albeit not identical, mechanisms are governing the metabolic adaptation to parturition [6,46,93]. These mechanisms include non-insulin dependent glucose uptake, increased maternal circulating epinephrine and norepinephrine, enhanced hepatic gluconeogenesis and direct sympathetic nervous system stimulation [6,46,93].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

227: Evidence for differential regulation of the adipokine visfatin in the maternal and fetal compartments in normal spontaneous labor at term

Mazaki‐Tovi

Romero

Vaisbuch

et al. 2009

American Journal of Obstetrics and Gynecology

View full text Add to dashboard Cite

Section: The Presence Of Spontaneous Labor At Term Is Associated Withmentioning

confidence: 99%

Section: The Presence Of Spontaneous Labor At Term Is Associated Withmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

227: Evidence for differential regulation of the adipokine visfatin in the maternal and fetal compartments in normal spontaneous labor at term

Mazaki‐Tovi

Romero

Vaisbuch

et al. 2009

American Journal of Obstetrics and Gynecology

View full text Add to dashboard Cite

“…The conventional view is that labor and delivery can be viewed as a moderate exercise [6, 30] and that similar, albeit not identical, mechanisms are governing the metabolic adaptation to parturition [6, 46, 93]. These mechanisms include non-insulin dependent glucose uptake, increased maternal circulating epinephrine and norepinephrine, enhanced hepatic gluconeogenesis and direct sympathetic nervous system stimulation [6, 46, 93]. …”

Section: Introductionmentioning

confidence: 99%

Evidence for differential regulation of the adipokine visfatin in the maternal and fetal compartments in normal spontaneous labor at term

Mazaki‐Tovi

Romero

Vaisbuch

et al. 2010

Journal of Perinatal Medicine

View full text Add to dashboard Cite

Objective Visfatin, a novel adipokine with metabolic and immunoregulatory properties, has been implicated in the regulation of fetal growth, as well as in preterm labor. A gap in knowledge is whether spontaneous labor at term is associated with changes in the maternal and fetal concentrations of visfatin. The aim of this study was to determine if the presence of labor at term is associated with alterations in maternal and neonatal plasma visfatin concentrations. Study design This cross-sectional study included 50 normal pregnant women at term and their appropriate-for-gestational age (AGA) neonates in the following groups: 1) 25 mother-neonate pairs delivered by elective cesarean section without spontaneous labor, and 2) 25 mother-neonate pairs who delivered vaginally following spontaneous labor. Maternal plasma and cord blood visfatin concentrations were determined by ELISA. Non-parametric statistics were used for analyses. Results 1) The median visfatin concentration was higher in umbilical cord plasma of neonates born following a spontaneous labor at term than that of those who were born by an elective cesarean section (p=0.02); 2) in contrast, the median maternal plasma visfatin concentration did not differ significantly between patients with and without labor (p=0.44); and 3) there was a significant correlation between umbilical cord plasma concentration of visfatin and both maternal visfatin concentration (r= 0.54, p=0.005) and gestational age at delivery (r= 0.58; p=0.002) only in the absence of labor. Conclusion Term labor is associated with increased fetal, but not maternal, circulating visfatin concentrations. Previous reports indicate that preterm labor leading to preterm delivery is characterized by an increase in maternal plasma concentrations of visfatin. The observations reported herein support the view that there are fundamental differences in the endocrine and metabolic adaptations in normal labor at term and preterm labor.

show abstract

“…Hypoxia and fetal hyperglycemia can increase the production of maternal and fetal lactate, resulting in metabolic acidosis (7) .…”

Section: Introductionmentioning

confidence: 99%

Measuring the energy spent by parturient women in fasting and in ingesting caloric replacement (HONEY)

Melo

Peraçoli

2007

Rev. Latino-Am. Enfermagem

View full text Add to dashboard Cite

Fetal and maternal energy metabolism during labor in relation to the available caloric substrate

Cited by 27 publications

References 44 publications

227: Evidence for differential regulation of the adipokine visfatin in the maternal and fetal compartments in normal spontaneous labor at term

227: Evidence for differential regulation of the adipokine visfatin in the maternal and fetal compartments in normal spontaneous labor at term

Evidence for differential regulation of the adipokine visfatin in the maternal and fetal compartments in normal spontaneous labor at term

Measuring the energy spent by parturient women in fasting and in ingesting caloric replacement (HONEY)

Contact Info

Product

Resources

About