Fetal and Maternal Metabolism of Estradiol During Pregnancy

Gurpide, Erlio; Schwers, Jean; Welch, Margaret T.; Wiele, Raymond L. Vande; Lieberman, Seymour

doi:10.1210/jcem-26-12-1355

Cited by 103 publications

(22 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This steroid is produced by the fetal liver only and found exclusively during human pregnancy 11 . Estetrol has been isolated in maternal urine as early as week 9 of gestation 12,13 .…”

Section: Introductionmentioning

confidence: 99%

Preventive effect of oral estetrol in a menopausal hot flush model

2008

View full text Add to dashboard Cite

show abstract

“…This steroid is produced by the fetal liver only and found exclusively during human pregnancy 11 . Estetrol has been isolated in maternal urine as early as week 9 of gestation 12,13 .…”

Section: Introductionmentioning

confidence: 99%

Preventive effect of oral estetrol in a menopausal hot flush model

2008

View full text Add to dashboard Cite

show abstract

“…This steroid is produced by the fetal liver only and found exclusively during human pregnancy 2 . Estetrol has been isolated in maternal urine as early as week 9 of gestation 3,4 .…”

Section: Introductionmentioning

confidence: 99%

Estrogenic uterovaginal effects of oral estetrol in the modified Allen–Doisy test

Heegaard

Holinka

Kenemans³

et al. 2008

Climacteric

View full text Add to dashboard Cite

show abstract

“…Estro gens synthesized by the placenta enter the maternal circulation preferentially. In fact, one study has shown that more than 90% of the estradiol and estriol formed in the trophoblast is secreted into the maternal compartment [18]. The same is true of pro gesterone formed in the trophoblast; 85% or more enters the maternal compartment [19], Moreover, a small proportion of the steroids produced in the placenta or found circulating in the maternal compartment reaches the fetal circulation due to the much greater size of the maternal compartment and their rapid clearance from maternal plasma [20,21].…”

Section: Discussionmentioning

confidence: 99%

Morphological Observations of the Fetal Rat Spleen during Prolonged Gestation

Thliveris¹,

Petriuk²,

Anderson³

et al. 1983

Cells Tissues Organs

View full text Add to dashboard Cite

The ultrastructure of splenic cells and frequency of cell types were examined in fetal rats during progesterone-induced (P23, 24, 25) and surgically-induced (S23, 24, 25) prolonged gestation, and compared to term (T) fetuses and newborn animals (N₁ N₂, N₃). Statistical analysis revealed an increase in numbers of erythroblasts and a decrease in numbers of neutrophils in post-term fetuses distinct from that seen in term and newborn animals. However, there were also significant differences between the post-term groups: the frequency of erythrocytes and total number of cells were higher in the drug-treated group, despite similar splenic weights in the two. The results are interpreted as a response by the spleen (increased erythropoiesis) to fetal hypoxia, which is known to exist during prolonged gestation.

show abstract

Fetal and Maternal Metabolism of Estradiol During Pregnancy

Cited by 103 publications

References 0 publications

Preventive effect of oral estetrol in a menopausal hot flush model

Preventive effect of oral estetrol in a menopausal hot flush model

Estrogenic uterovaginal effects of oral estetrol in the modified Allen–Doisy test

Morphological Observations of the Fetal Rat Spleen during Prolonged Gestation

Contact Info

Product

Resources

About