Fetal and maternal responses to high feed intake from day 29 to 45 of gestation (1997)

Musser, R.E.; Smith, Joseph Wayne; Burum, L.L.; Samland, C.J.; Davis, Duane L.; Goodband, Robert D.; Tokach, Michael D.; Nelssen, Jim L.; Rathbun, T.; Dritz, Steven S.

doi:10.4148/2378-5977.6538

Cited by 2 publications

(3 citation statements)

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“…Concentration of serum IGF‐I increased with the enhanced feed intake levels. This finding supports the previous reports (Musser et al. 1997, 2004).…”

Section: Discussionsupporting

confidence: 94%

“…Much of the research on the feed intake and pregnancy has been focused on the effect of feed intake on the secretion of sows’ hormone and the relationship between hormones and embryonic survival rate. Feed intakes significantly affect the concentration of insulin‐like growth factor‐I (IGF‐I), leptin and progesterone (Musser et al. 1997, 2004; Ashworth et al.…”

Section: Introductionmentioning

confidence: 99%

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The Level of Feed Intake Affects Embryo Survival and Gene Expression During Early Pregnancy in Gilts

Xu¹,

Wu²,

Guo³

et al. 2009

Reproduction in Domestic Animals

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Appropriate feed intake level would enhance embryo survival. This study investigated the relationship among feed intake level, embryo survival, hormone secretion and mRNA expression. Fifty-four Landrace x Yorkshire crossbred gilts were allotted to three treatment groups of high (H, 2 x maintenance), medium (M, 1.2 x maintenance) and low (L, 0.6 x maintenance) after mating, to study the effect of feed intake levels on embryo survival, hormone secretion and mRNA expression of leptin, obesity receptor (ob-R), signal transducer and activator of transcription-3 (STAT3), DNA methyltransferase 1 (DNMT1), retinol-binding protein 4 (RBP4), fibroblast growth factor receptor 2 (FGFR2) and progesterone receptor (PGR) in embryos. Blood samples and embryos were collected for hormone concentrations determination and gene expression analysis. Slaughter weight, total weight gain and net weight gain were affected (p < 0.05) by dietary treatment. Embryonic survival was 80.23% and 78.45% in M group on days 25 and 35 of pregnancy, respectively, and was greater (p < 0.05) in M than H and L groups. Serum insulin-like growth factor-I and leptin concentrations enhanced (p < 0.05) with the increased feed intake, but progesterone concentrations were lower (p < 0.05) in H than M and L groups and no difference (p > 0.05) between M and L on days 25 and 35 of pregnancy. Real-Time PCR indicated that gene expression pattern of leptin, ob-R, STAT3 and DNMT1 were the highest (p < 0.05) in H group on days 25 and 35 of pregnancy. Transcript expression level of RBP4 and FGFR2 were the highest (p < 0.05) in M group on days 25 and 35 of pregnancy. Significantly higher (p < 0.05) expression of PGR was observed in L group on day 25 and in M group on day 35 of pregnancy. Our data suggest that 1.2 x maintenance feed intake level promoted the appropriate hormone secretion and enhanced genes expression in RBP4, FGFR2 and PGR, and thus resulted in better embryo survival compared with the high and low groups.

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“…Concentration of serum IGF‐I increased with the enhanced feed intake levels. This finding supports the previous reports (Musser et al. 1997, 2004).…”

Section: Discussionsupporting

confidence: 94%

Section: Introductionmentioning

confidence: 99%

The Level of Feed Intake Affects Embryo Survival and Gene Expression During Early Pregnancy in Gilts

Xu¹,

Wu²,

Guo³

et al. 2009

Reproduction in Domestic Animals

View full text Add to dashboard Cite

show abstract

“…Studies showed that serum concentrations of IGF‐I and insulin would increase with increasing feed allowance level, but the concentration of GH would decrease (Buonomo and Baile, 1991; Musser et al., 1997, 2004). In our study, gilts fed 2 × maintenance feeding level had lower serum and uterine GH concentration.…”

Section: Discussionmentioning

confidence: 99%

Effect of feeding allowance level on embryonic survival, IGF‐1, insulin, GH, leptin and progesterone secretion in early pregnancy gilts

Wu¹,

Ai-rong²,

Lin

et al. 2009

Animal Physiology Nutrition

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The present experiment was conducted to evaluate the effects of feeding allowance level on embryonic survival, uterine development and reproductive hormone secretion in early gestation gilts. A total of 54 F1 crosses of Landrace x Large white gilts were randomly allocated to three treatment groups of high (H, 2 x maintenance), medium (M, 1.2 x maintenance) and low (L, 0.6 x maintenance) feeding level after mating. Blood samples and uterine flushings were collected on day 12, 25 and 35 of pregnancy, and embryonic survival rate was estimated. Concentrations of insulin-like growth factor I (IGF)-1, insulin, growth harmone (GH), leptin and progesterone in serum and uterine flushings were determined by enzyme-linked immunosorbent assay. Embryonic survival was affected by dietary treatment; total number of viable embryos and embryo survival of group M were higher than other groups in the early pregnancy (p < 0.05). Greater foetal weight in M gilts was achieved when gestation advanced to day 35 (p < 0.05), though there was no difference on day 25 of pregnancy among treatments. No appreciable differences were observed in the crown-rump length on day 25 and 35 of pregnancy among groups. Greater weight of uterus and products of conception were identified in M gilts compared with group H and L (p = 0.024 and p = 0.005, respectively) on day 25 of pregnancy. The hormone level was greatly affected by feeding allowance level. In serum, concentrations of IGF-1, leptin and insulin tended to be greater in H than in M and L during the early gestation, while concentrations of GH were greater in M and progesterone were the lowest in H. At the same time, feed allowance level affected the concentration of IGF-1, insulin, GH, leptin and progesterone in uterine flushings. These data demonstrated that feed allowance level after mating has important consequence on embryo survival, embryo development and uterine development, possibly mediated by nutrition level inducing changes in concentrations of reproductive hormones and/or intermediary metabolites in early pregnancy.

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Fetal and maternal responses to high feed intake from day 29 to 45 of gestation (1997)

Cited by 2 publications

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The Level of Feed Intake Affects Embryo Survival and Gene Expression During Early Pregnancy in Gilts

The Level of Feed Intake Affects Embryo Survival and Gene Expression During Early Pregnancy in Gilts

Effect of feeding allowance level on embryonic survival, IGF‐1, insulin, GH, leptin and progesterone secretion in early pregnancy gilts

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