Fetal Lymphatic Malformations: More Variable Than We Think?

Oliver, Edward R.; Coleman, Beverly G.; DeBari, Suzanne E.; Victoria, Teresa; Looney, Devon M.; Horii, Steven C.; Moldenhauer, Julie S.; Langer, Jill E.; Howell, Lori J.; Pawel, Bruce; Adzick, N. Scott

doi:10.7863/ultra.16.04071

Cited by 20 publications

(16 citation statements)

References 24 publications

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“…At US, these malformations appear as multiseptated cystic lesions, lacking solid components, vascularity and calcifications. However, a recent review has described a greater imaging variability than previously reported, including mixed cystic/solid lesions and occasional calcifications [17].…”

Section: Congenital Lymphatic Malformationsmentioning

confidence: 92%

“…Lymphatic malformation is the most often detected vascular malformation in the fetus and the most widely described in the literature [4,[15][16][17][18]. The reported incidence is 1:2,000-6,000 cases in live births, with a slight male predominance [16].…”

Section: Congenital Lymphatic Malformationsmentioning

confidence: 99%

“…The reported incidence is 1:2,000-6,000 cases in live births, with a slight male predominance [16]. They can occur in any location, but are much more often located in the neck (75%) and the axilla (20%) than in the abdomen (2%), limbs (2%) and mediastinum (1%) [4,15,17]. They are usually classified as microcystic (cysts <2 cm in size), macrocystic (>2 cm) and mixed lesions.…”

Section: Congenital Lymphatic Malformationsmentioning

confidence: 99%

“…They are usually classified as microcystic (cysts <2 cm in size), macrocystic (>2 cm) and mixed lesions. Macrocystic lesions are usually more voluminous and therefore easier to detect in utero than microcystic ones [17]. At US, these malformations appear as multiseptated cystic lesions, lacking solid components, vascularity and calcifications.…”

Section: Congenital Lymphatic Malformationsmentioning

confidence: 99%

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Contribution of magnetic resonance imaging to the prenatal diagnosis of common congenital vascular anomalies

et al. 2021

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Background Screening ultrasound (US) has increased the detection of congenital vascular anomalies in utero. Complementary magnetic resonance imaging (MRI) may improve the diagnosis, but its real utility is still not well established. Objectives We aimed to describe the imaging findings on prenatal US and MRI of the most frequent congenital vascular anomalies (lymphatic malformations and congenital hemangiomas) to assess the accuracy of prenatal US and MRI exams for diagnosis and to evaluate the relevance of the additional information obtained by complementary fetal MRI. Materials and methods All confirmed postnatal congenital vascular anomalies detected in the last 10 years at 3 university hospitals were retrospectively identified. The prenatal diagnosis was compared with the final diagnosis for both methods and the clinical relevance of additional MRI information was evaluated. A second MRI in advanced pregnancy was performed in fetuses with lesions in a sensitive anatomical location and the clinical relevance of the additional information was evaluated. Results Twenty-four cases were included in the study, 20 lymphatic malformations and 4 hemangiomas. MRI slightly improved the diagnosis of lymphatic malformation, 85% vs. 80% at US, especially for abdominal lesions. Both methods had a low identification rate (25%) for tumors. MRI performed late in five fetuses with lymphatic malformation allowed optimized management at birth. Conclusion MRI improves the diagnosis of congenital lymphatic malformations whereas hemangiomas remain difficult to identify in utero. The main role of MRI is to provide high-defined anatomical data to guide management at birth.

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Section: Congenital Lymphatic Malformationsmentioning

confidence: 92%

Section: Congenital Lymphatic Malformationsmentioning

confidence: 99%

Section: Congenital Lymphatic Malformationsmentioning

confidence: 99%

Section: Congenital Lymphatic Malformationsmentioning

confidence: 99%

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Contribution of magnetic resonance imaging to the prenatal diagnosis of common congenital vascular anomalies

et al. 2021

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“…Yet, it has become well known that lymphatic malformations may have a very complex and atypical appearance. Oliver et al describe a greater than previously reported variability in the prenatal sonographic appearance of these lesions 75 . Authors introduce a new classification of lymphatic malformations that categorizes the lesions by their internal architecture.…”

Section: Vascular Malformations Spectrummentioning

confidence: 99%

Fetal brain, head, and neck tumors: Prenatal imaging and management

2020

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Fetal tumors represent an infrequent pathology when compared to congenital malformations, although their true incidence may be underestimated. A variety of benign and malignant neoplasms may occur anywhere in the neural axis. Imaging plays an important role in the fetal tumor diagnosis and evaluation of their resultant complications. Discovery of a fetal mass on obstetric ultrasound necessitates further evaluation with prenatal magnetic resonance imaging (MRI). New MR sequences and new applications of existing techniques have been successfully implemented in prenatal imaging. A detailed assessment may be performed using a variety of MR. Fetal tumors may be histologically benign or malignant, but their prognosis generally remains poor, especially for intracranial lesions. Unfavorable tumor location or heightened metabolic demands on a developing fetus may result in severe complications and a fatal outcome, even in cases of benign lesions. Nowadays, prenatal treatment focuses mainly on alleviation of secondary complications caused by the tumors. In this article we review congenital tumors of the brain, face, and neck encountered in prenatal life, and discuss diagnostic clues for appropriate diagnosis.

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