Fetal-Maternal Morbidity and Mortality as Outcome of Premature Rupture of Membrane (PROM)

Abstract

Background: The risk of prenatal morbidity and death associated with PPROM is more than 20%, and the outcome is significantly impacted by the gestational age at delivery. Objectives: The goal of the study was to determine the fetal/maternal outcomes for pregnant patients at Al-Azhar University Hospitals in Cairo who had PPROM as well as any possible risk factors for adverse fetal/neonatal outcomes. Patients and Method: At the Al-Azhar University Hospitals in Cairo, cross-sectional research including 48 women with PROM was done. The trial was from February 2022 to August 2022. All patients were received a thorough history, a general examination, and laboratory tests. Results: In terms of fetal result, 56.3% of infants experienced poor outcomes, such as fetal death and ICU admission, compared to 43.7% of infants who experienced positive outcomes (alive & well).The multivariate analysis revealed that later gestational age at PPROM (OR 0.7 CI 0.22 -0.91) and gush type of PPROM (OR 1.6 CI 1.2 -3.2), history of chorioamnionitis (OR 17.5 CI 13.9 -129.7), delivery by CS (OR 3 CI 2.45 -4.6), and women employment (OR 1.7 CI 1.3 -3.3) were significant independent. Conclusion: PPROM necessitates adequate prenatal care and therapy since it is linked to fetal/maternal morbidity and death.