1992
DOI: 10.1007/978-1-4615-3428-0_58
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Fetal Oxygenation in Chronic Maternal Hypoxia; What’s Critical?

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Cited by 15 publications
(5 citation statements)
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“…Independent prospective acute animal studies in the Netherlands confirmed the existence of a critical threshold value of FSpO, for the development of fetal acidosis caused by hypoxia of 30% (Nijland, Jongsma, Nijhuis, van den Berg, & Oeseburg, 1995). Observations with fetal pulse oximetry during human labors demonstrated that a value of FSpO, of 30% represents the 3rd percentile of fetal FSpO, values recorded during normal-outcome labor (Oeseburg et al, 1992).…”
Section: The Critical Threshold Value For Fetal Oxygen Saturation Detmentioning
confidence: 85%
“…Independent prospective acute animal studies in the Netherlands confirmed the existence of a critical threshold value of FSpO, for the development of fetal acidosis caused by hypoxia of 30% (Nijland, Jongsma, Nijhuis, van den Berg, & Oeseburg, 1995). Observations with fetal pulse oximetry during human labors demonstrated that a value of FSpO, of 30% represents the 3rd percentile of fetal FSpO, values recorded during normal-outcome labor (Oeseburg et al, 1992).…”
Section: The Critical Threshold Value For Fetal Oxygen Saturation Detmentioning
confidence: 85%
“…Estudos experimentais e em humanos têm sido desenvolvidos para o estabelecimento do nível crítico de SpO 2 fetal. Oeseburg et al 17 e Nijland et al 16 realizaram uma série de pesquisas neste sentido em fetos de ovelha. Reduzindo o volume de oxigênio materno inspirado ou reduzindo o fluxo sangüíneo uterino materno, por oclusão vascular, estes autores demonstraram que, sob uma saturação de O 2 no sangue fetal igual ou superior a 30%, o seu metabolismo aeróbico era mantido.…”
Section: Discussionunclassified
“…A systematic and rigorous scientific process was used to determine the critical threshold of 30% FSp02 for the fetus during labor (Porter, 2000;Swedlow, 2000). This process included a retrospective search of the scientific literature for evidence demonstrating the existence of a critical threshold for fetal oxygen saturation (Richarson, Carmichael, Homan & Patrick, 1992;Swedlow, ZOOO), prospective research demonstrating the existence of that threshold in well-designed animal studies in a standard obstetric model (Nijland, Jongsma, Nijhuis, van de Berg & Oeseburg, 1995), retrospective examination of the distribution of FSp02 values observed in human fetuses experiencing normal-outcome labor and definition of the threshold at or below the fifth percentile of the normal distribution (Oeseburg et al, 1992), and prospective study for the presence of acceptable predictive agreement between FSp02 and fetal scalp pH (considered the gold standard method of assessing fetal well-being) (Dildy, Thorp, Yeast & Clark, 1996;Kuhnert, Seelbach-Gobel, Butterwegge, 1998;Seelbach-Gobel, Heupel, Kuhnert, Butterwegge, 1999). Based on these data, a 30% FSp02 value is an accurate critical threshold for normal versus hypoxemic values for the fetus during labor.…”
Section: Evidence For a Fetal $ 0 2 Critical Threshold Of 30%mentioning
confidence: 99%