Fetal ventriculomegaly: diagnostic, ethical and semantic considerations

Guibaud, Laurent; Lacalm, Audrey; Rault, E.

doi:10.1007/s00381-017-3500-4

Cited by 5 publications

(4 citation statements)

References 6 publications

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“…is related to diffuse polymicrogyria in CMV infection [12]. Second, degree of ventriculomegaly (from mild to severe) is clearly not correlated to prognosis which is related to the underlying parenchymal lesion [13]. Therefore, ventriculomegaly "per se" should not be considered a prognostic feature.…”

Section: Discussionmentioning

confidence: 99%

“…Similarly, “smooth aspect of the cortical surface” should not be assimilated to “lissencephaly” since MR and pathological examination clearly demonstrate that such an aspect is related to diffuse polymicrogyria in CMV infection [12]. Second, degree of ventriculomegaly (from mild to severe) is clearly not correlated to prognosis which is related to the underlying parenchymal lesion [13]. Therefore, ventriculomegaly “per se” should not be considered a prognostic feature.…”

Section: Discussionmentioning

confidence: 99%

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Predicting Outcome of Congenital Cytomegalovirus Infection by Differentiating and Revisiting Severe versus Mild Prenatal Imaging Features

Massoud¹,

Chollet²,

Cabet³

et al. 2023

Fetal Diagn Ther

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Introduction Our objective was to evaluate the outcome of fetuses with first and second-trimester fetal cytomegalovirus infection (CMVi) according to prenatal imaging patterns, especially fetuses presenting with mild imaging features (MF), being currently of uncertain prognosis. Material and Methods Among a retrospective study on 415 suspected CMVi cases, 59 cases were confirmed CMVi. Among prenatal imaging features, microcephaly, cortical disorder and cerebellar hypoplasia as well as severe IUGR and fetal hydrops were considered as severe imaging features (SF). Others imaging features were considered as mild imaging features (MF).Postnatal outcome was classified as "normal outcome", “mild sequelae” characterized mainly by sensorineural disorder (SND) and “severe sequelae” characterized by cognitive impairment. Results Only first-trimester (T1) and second-trimester (T2) CMVi cases were included in our study (n=49) since all third-trimester cases (n=10) had normal imaging and outcome. Sixteen fetuses had normal prenatal imaging and normal outcome , except one showing SND. Abnormal ultrasound findings were present in 33 fetuses, including SF noted in 16 fetuses, related exclusively to first trimester CMVi and 17 fetuses with MF (13 during first trimester and 4 during second trimester). Termination of pregnancy (TOP) was performed in 18 cases. Twelve first-trimester infected fetuses presented SF, whereas 6 fetuses (T1: n=5, T2: n=1) presented isolated MF. Four foetal deaths were encountered. Live-born babies with abnormal imaging included 10 foetus with MF and one with SF. Among the 10 live babies with isolated MF, SND was encountered in 5 cases, whereas 5 children demonstrated normal outcome. Overall, 50% of our babies showing MF suffered from SND. No case of cognitive disorders were reported in babies showing only MF. Conclusion SF were encountered only in first-trimester CMVi and should be distinguished from MF. Among our 10 live babies with prenatal MF following first or second-trimester infection, 50% showed SND whereas none presented severe sequelae. In 16 foetuses displaying normal foetal imaging, SND was encountered in one first-trimester case (6%).

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Predicting Outcome of Congenital Cytomegalovirus Infection by Differentiating and Revisiting Severe versus Mild Prenatal Imaging Features

Massoud¹,

Chollet²,

Cabet³

et al. 2023

Fetal Diagn Ther

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“…Se establece un plano en el cual también se visualiza el CSP y las astas anteriores del sistema ventricular (plano transventricular). Se realiza con la intención de descartar dilataciones del sistema ventricular cerebral (ventriculomegalia, signo muy frecuente y común a muchas patologías cerebrales) (3)(4)(5)(6)(7)(8)(9)(10) . Los reparos anatómicos para su correcta medida involucran la identificación de la cisura parieto-occipital, que marca el lugar donde se realiza la medida in to in de las paredes del atrio ventricular (1,2) ; se sigue manteniendo el valor clásico de 9,9 mm como dogma de normalidad (3)(4)(5) (figuras 1B y 2B).…”

Section: Evaluación Del Cerebro Fetalunclassified

Evaluación del cerebro fetal: nuevas herramienta

Paredes

Malinger

2021

Rev peru ginecol obstet.

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La evaluación del cerebro fetal es un punto imprescindible en el ultrasonido obstétrico, por la gran cantidad de malformaciones que pueden ser diagnosticadas. La guía de ISUOG nos brinda los cortes elementales para la sospecha de la patología cerebral; pero, podemos ampliar y mejorar nuestro ultrasonido con la visualización de estructuras fácilmente reproducibles, tales como el complejo anterior, cuerpo calloso, cisura de Silvio y el cuarto ventrículo. Presentamos algunas herramientas para complementar la evaluación del cerebro fetal.

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“…Rhombencephalosynapsis (RES) is a rare cerebellar malformation defined by partial or complete agenesis of the vermis and fusion of the cerebellar hemispheres and dentate nuclei [1][2][3][4][5].…”

Section: Introductionmentioning

confidence: 99%