Feticide Does Not Modify Duration of Labor Induction in Cases of Medical Termination of Pregnancy

Silva, Luciana Vivas; Cecatti, José Guilherme; Silva, João Luiz Pinto e; Amaral, Eliana; Barini, Ricardo

doi:10.1159/000116740

Cited by 13 publications

(7 citation statements)

References 16 publications

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“…Silva et al [19] reported that CNS abnor- malities (60%) were the most common indication as comparable with our results. However, the proportion of CNS abnormalities was relatively lower in our population.…”

Section: Discussionsupporting

confidence: 93%

“…However, some previous data do not support these results. Although Silva et al [19] found shorter I-to-A interval in the feticide group compared with that of the non-feticide group (mean duration of 42.9 vs. 53.2 h), the difference was not statistically significant. Heterogeneity in medical treatment may have led to a conservative bias in their study and precluded the real effect of the feticide.…”

Section: Discussionmentioning

confidence: 72%

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The Utility of Feticide Procedure to Shorten the Induction-to-Abortion Interval in Medical Abortion

Akkurt

Yavuz

et al. 2018

Gynecol Obstet Invest

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Aim: To evaluate the effect of intracardiac potassium chloride feticide procedure (FP) on the induction-to-abortion (I-to-A) interval for various indications in the termination of pregnancy. Method: Medically indicated abortions between 17 and 28 weeks’ gestation were retrospectively evaluated and allocated into 2 groups: Cases with (group 1, n = 58) or without an FP (group 2, n = 60). I-to-A intervals were compared across the groups, considering different baseline parameters and fetal abnormality categories. Results: There were no differences among the groups except in gestational age (GA; mean, 21.2 vs. 19.6 weeks, p = 0.01) in group 1. Overall, the I-to-A interval was shorter (900 ± 233 vs. 1,198 ± 375 min, p = 0.001) and prolonged medical abortion (I-to-A interval > 48 h) was less common (2% vs. 6%, p = 0.03) in group 1. The facilitating effect of FP persisted when indications were categorized as central nervous system, chromosomal, other structural abnormalities, and unclassified conditions. Logistic regression analyses demonstrated the following features to be associated with expulsion of fetus after 24-h: (1) advanced GA (> 24 week; aOR 6.9, 95% CI 3.24–14.72), (2) central nervous system abnormalities (aOR 5.3, 95% CI 2.6–11.4), (3) lack of feticide (aOR 3.67, 95% CI 2.24–10.72). Conclusion: FPs seem to shorten the I-to-A interval and decrease prolonged I-to-A interval rates. This facilitating effect remains unchanged for various medical indications.

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Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 72%

The Utility of Feticide Procedure to Shorten the Induction-to-Abortion Interval in Medical Abortion

Akkurt

Yavuz

et al. 2018

Gynecol Obstet Invest

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“…In one study, the effect of feticide on the duration of labour induction was examined retrospectively and there was no significant difference noticed in the outcome except that the group with feticide tend to have more procedure in the form of manual extraction of placenta or uterine curettage or both (82.9 versus 65.6%, P = 0.01) [22]. This study differs from the other studies above in that it is not stratified according to the method of termination but rather whether feticide was performed or not.…”

Section: Resultsmentioning

confidence: 99%

To Compare the Methods of Pregnancy Termination for Fetal Abnormality in the First and Second Trimesters

Wong

2012

ISRN Obstetrics and Gynecology

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Fetal abnormality is a major cause of termination of pregnancy and preservation of the fetus is important for confirmation of the diagnosis. Various regimes have been reported for termination of pregnancy for fetal abnormality in the first and the second trimesters. In this paper, we compare those regimes that allow preservation of the fetus, in terms of the efficacy in expulsion of the fetus, the factors and the side effects.

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“…There was no significant difference between the two groups in terms of complications at the 12 th , 24 th , and 48 th hours21. In one study, the effect of feticide on the duration of labor induction was examined retrospectively and there was no significant difference noticed in the outcome except that the group with feticide tended to have more procedures in the form of manual extraction of placenta or uterine curettage or both (82.9 vs. 65.6%, P = 0.01)22. The results also showed that performing feticide procedures had no effect on the termination duration.…”

Section: Discussionmentioning

confidence: 99%

Does feticide shorten termination duration in second trimester pregnancy terminations?

Sık¹,

Bilecan²,

Kumbasar³

et al. 2019

Afr H. Sci.

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Backround A retrospective (case-controlled) study was conducted with the aim of identifying the effect of the use of misoprostol on termination time in patients who did and did not undergo feticide procedures in second trimester pregnancy terminations. Methods The sampling of the study consisted of 144 pregnant women who were diagnosed as having major fetal anomalies incompatible with life, and were recommended for termination of pregnancy. The investigation showed that feticide procedures were performed for 99 women, and feticide procedures were not performed for 45 women. Misoprostol protocol was administered for 48 hours in the termination period; whether the feticide procedure directly affected the termination duration in patients who did and did not undergo feticide was evaluated. Results Abortion/birth was achieved in 103 (71.5%) women during the first 48 hours. There was no significant difference between the termination duration of the misoprostol protocol among the women who did and did not undergo feticide. There was no significant difference between the termination durations and fetal biometric measurements (BPD, HC) except head diameters (p=0.020 and p=0.015). Conclusions The misoprostol protocol is shown to be effective and safe for the termination of pregnancies during the second trimester. Feticide has no affect on the duration of termination.

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Feticide Does Not Modify Duration of Labor Induction in Cases of Medical Termination of Pregnancy

Cited by 13 publications

References 16 publications

The Utility of Feticide Procedure to Shorten the Induction-to-Abortion Interval in Medical Abortion

The Utility of Feticide Procedure to Shorten the Induction-to-Abortion Interval in Medical Abortion

To Compare the Methods of Pregnancy Termination for Fetal Abnormality in the First and Second Trimesters

Does feticide shorten termination duration in second trimester pregnancy terminations?

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