Feto-maternal outcome in patients with HELLP and partial HELLP syndrome: a prospective 10 year study in Shri Guru Ram Rai Institute of Medical and Health Sciences, Uttarakhand, India

Tandon, Archna; Chaudhari, Priyanka; Gupta, Vineeta; Ramola, Monika

doi:10.18203/2320-1770.ijrcog20162986

Cited by 2 publications

(4 citation statements)

References 6 publications

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“…Study by Tandon et al also concluded the same. 5 Headache was the most frequently recorded symptom in the present study with similar observations by Yildrim et al and Turgut et al 6,7 In the present study, frequency of vaginal deliveries was 52.72% and 81.81% in preeclampsia and HELLP groups respectively. Shafika Banoo et al, 2007 reported similar trend towards vaginal delivery in HELLP syndrome-60%.…”

Section: Maternal Outcomesupporting

confidence: 91%

“…The study result was comparable to that by Tandon et al -1.8kg vs 2.47kg. 5 Low birth weight with a mean of 1.8kg in HELLP group as compared to 2.7kg in preeclampsia group was also observed in study in 2018 by Kongwattanakul et al 15 ARDS was the most common complication, 29.09% vs 12.72% in HELLP and preeclampsia groups. Frequency of ARDS was also higher in HELLP than in preeclampsia in study by Turgut et al, 2010 -13.3% vs 9.1%.…”

Section: Perinatal Outcomementioning

confidence: 59%

“…Similar incidence was observed by Tandon et al-12.72% vs 2.09%. 5 The overall incidence of complications was more in HELLP syndrome -40% than in preeclampsia group 14.55%. These findings are in accordance with all of the studies compared with Yildrim et al 6 39 patients (70.9%) of HELLP needed transfusion of blood or blood products.…”

Section: Maternal Outcomementioning

confidence: 87%

“…Frequency of preeclampsia and HELLP did not vary according to gravida status of the woman, 30.9% were primigravida and 69.1% were multigravida.The gestational age in HELLP syndrome was 36.77 weeks and in preeclampsia 35.83 weeks. Tandon et al, 2016 also observed preeclampsia at mean of 36.4 weeks and HELLP at mean 35.3 weeks 5. Preterm delivery <34 weeks was observed by Yildrim et al and Turgut et al…”

mentioning

confidence: 88%

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Maternal and perinatal outcome in patients of preeclampsia with and without HELLP syndrome

Madge

Seth

2019

Int J Reprod Contracept Obstet Gynecol

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Background: Preeclampsia is seen in about 5-10% of all pregnancies and HELLP Syndrome occurs in 6-12% of these patients. Both are known to increase maternal and perinatal morbidity. The study aims to provide a comprehensive view of these myriad outcomes in the mother and neonate both, in each of the groups. It also compares the incidence of such outcomes in mother and child, in preeclampsia only and in those complicated by HELLP syndrome.Methods: This prospective, observational, comparative study was conducted at a tertiary referral centre. 55 patients with preeclampsia were compared with 55 patients with HELLP syndrome. The relevant clinical features, laboratory investigations and the maternal and perinatal outcomes along with the incidence were studied and results analyzed.Results: Significant differences were observed in laboratory parameters and duration of ICU stay in patients with preeclampsia and patients with HELLP syndrome. Incidence of maternal complications and need for blood transfusion was greater in HELLP syndrome. Only marginal differences were observed in birth weight, NICU admission rates and neonatal mortality rates.Conclusions: HELLP syndrome is associated with increased maternal morbidity and mortality as compared to preeclampsia. Neonatal outcomes appear to be influenced; only marginally, by HELLP syndrome, nevertheless, their incidence is more than in preeclampsia. Aggressive treatment for pregnant women appears to decrease the maternal mortality rate.

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Section: Maternal Outcomesupporting

confidence: 91%

Section: Perinatal Outcomementioning

confidence: 59%

Section: Maternal Outcomementioning

confidence: 87%

mentioning

confidence: 88%

See 2 more Smart Citations

Maternal and perinatal outcome in patients of preeclampsia with and without HELLP syndrome

Madge

Seth

2019

Int J Reprod Contracept Obstet Gynecol

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Feto-Maternal Outcome in Hellp Syndrome

Siddiqui

Saxena

Gupta

2021

IJAR

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Background: HELLP Syndrome is a serious obstetric complication in pregnancy characterised by haemolysis, elevated liver enzymes and low platelet count. Incidence is 0.5-0.9% of all pregnancies and in 10-20% of cases with severe preeclampsia (PE) and eclampsia. Aim of the present study is to evaluate the incidence, demographic and clinical prole; and maternal and perinatal outcome in women with HELLP syndrome. Methods: All women with hypertension with 28 weeks of gestation admitted to labour room in a single unit of tertiary care hospital at Government medical College Kota, Rajasthan from January 2019 to June 2020 and fullled the inclusion criteria. Incidence of HELLP syndrome was 1.9% of total deliveries and Results: 15.3% of total HDP cases. Out of 50 cases of HELLP syndrome, 62% belonged to class III, 22% to class II and 16% to class I of Mississippi classication. Mean age of patients of HELLP syndrome in present study was 24.72 4.18 years. 32 (64%) were primigravida while 18 (36%) were gravida two or more. Mean gestational age in study group was 35.98+ -3.33 week. Maternal mortality was seen in 6 (12%) cases and most common cause attributed to MODS 4 (66.67%). Conclusions: HELLP Syndrome is a severe variant and a dreadful complication of PE and eclampsia, it needs early diagnosis which is based upon clinical and laboratory ndings and timely intervention in the form of termination of pregnancy to arrest further progress of pathophysiology leading to complications.

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Feto-maternal outcome in patients with HELLP and partial HELLP syndrome: a prospective 10 year study in Shri Guru Ram Rai Institute of Medical and Health Sciences, Uttarakhand, India

Cited by 2 publications

References 6 publications

Maternal and perinatal outcome in patients of preeclampsia with and without HELLP syndrome

Maternal and perinatal outcome in patients of preeclampsia with and without HELLP syndrome

Feto-Maternal Outcome in Hellp Syndrome

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