“…6) Third, bFGF was given in vitro after irradiation in the present study, while previous studies that indicated protective effects were predominantly obtained in in vivo animal studies. 6,7,9,16) For example, Gallicchio et al, 6) demonstrated that when combined with adherent cell-depleted normal murine marrow cells, FGF increased the number of both day 9 and day 12 spleen CFUs from lethally irradiated animals. In adherent cell depleted murine and human marrow cultures, the addition of FGF showed synergistic activity in combination with the optimal concentration of GM-colony-stimulating factor (CSF) for CFU-GM.…”