Fibres for wound dressings based on mixed carbohydrate polymer fibres

Miraftab, Mohsen; Qiao, Q.; Kennedy, John F.; Anand, Subhash; Groocock, M.R.

doi:10.1016/s0144-8617(03)00108-5

Cited by 64 publications

(29 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These dressings include cellulose (Backdahl et al 2006;Wiegand et al 2006;, xerogels (Szczesniak and Kubis 1993), charcoal cloth (Wollina et al 2006), alginates (Hashimoto et al 2004;Edwards et al 2003), chitosan (Kato et al 2003) and hydrogels (Kashyab et al 2005;Kirker et al 2002). Carbohydrate-based dressings have afforded properties as absorbency, ease of application and removal, bacterial and odor protection, fluid balance, occlusion, and elasticity (Miraftab et al 2003;Wiseman et al 1992). This paper has reviewed and shown new findings on the use of cellulose tethered ions to promote wound healing by positively influencing molecular events associated with the inflammatory and hemostatic phases of wound healing.…”

Section: Discussionmentioning

confidence: 99%

Positively and negatively charged ionic modifications to cellulose assessed as cotton-based protease-lowering and hemostatic wound agents

et al. 2009

View full text Add to dashboard Cite

Recent developments in cellulose wound dressings targeted to different stages of wound healing have been based on structural and charge modifications that function to modulate events in the complex inflammatory and hemostatic phases of wound healing. Hemostasis and inflammation comprise two overlapping but distinct phases of wound healing wherein different dressing material properties are required to bring pathological events under control when they present as a result of trauma or chronic wounds. Thus, we have designed cellulose wound dressings with properties that function through modified fiber surface properties to lower protease levels in the chronic wound and promote clotting in hemorrhaging wounds. With this in mind three finishing chemistries utilizing traditional paddry-cure approaches were explored for their potential to confer charged properties to cotton dressings. Cellulose dressings designed to remove cationic serine proteases from highly exudative chronic wounds were created to present negatively charged fibers as an ion exchange mechanism of proteaselowering. Phosphorylated cotton and polycarboxylic acid crosslinked cotton were prepared to examine their ability to remove human neutrophil elastase (HNE) from surrogate wound fluid. A cellulose phosphorylation reaction utilizing sodium hexametaphosphate: urea was explored to optimize cellulose phosphorylation as a function of HNE sequestration efficacy. Acid catalyzed cross linking of cellulose with butane-tetracarboxylic acid also resulted in a negatively charged dressing that removed HNE from solution more effectively than phosphorylated cellulose. Collagenase sequestration was also assessed with phosphorylated cellulose and polycarboxylic acid cross linked cellulose derivatives. Butanetetracarboxylic acid and phosphorylated cellulose functioned to remove collagenase from solution most effectively. Cellulose dressings designed to accelerate thrombosis and aggregation of blood platelets were prepared with a view to examining derivatized cotton fibers bearing a net positive charge to promote hemostasis. Cellulose and chitosan dressings bearing an aminoglucan functionality were created by grafting chitosan on cotton and preparing aminized cotton. The preparation of chitosan-grafted cotton dressings was completed with a citric acid grafting onto cellulose. Aminized cotton was functionalized as an ethylamino-ether cellulose derivative. The chitosangrafted and aminized cotton demonstrated a dose response gelling of citrated sheep blood.

show abstract

Section: Discussionmentioning

confidence: 99%

Positively and negatively charged ionic modifications to cellulose assessed as cotton-based protease-lowering and hemostatic wound agents

et al. 2009

View full text Add to dashboard Cite

show abstract

“…18 19 By calcination of the alginate-based materials, the resultant carbon portion not only have mesopores and macropores, but also display excellent conductivity. [20][21][22][23][24][25] In the present study, we show a large-scale synthesis of nanostructured SnO 2 /C microfibers by using wet-spinning technique and thermal decomposition. SEM and TEM micrographs show that SnO 2 nanoparticles with a diameter of 10-15 nm were dispersed in the nanoporous carbon matrix.…”

Section: Introductionmentioning

confidence: 99%

Synthesis of Nanostructured SnO₂/C Microfibers with Improved Performances as Anode Material for Li-Ion Batteries

Yin

Xin²,

Wan³

et al. 2012

j nanosci nanotechnol

View full text Add to dashboard Cite

Nanostructured SnO2/C microfibers were prepared by thermal decomposition of tin alginate fibers produced via wet-spinning technique. Results of X-ray diffraction and scanning electron microscopy show that the as-obtained SnO2/C microfibers consist of nano-sized SnO2 crystals with a mean diameter of 10-15 nm. Transmission electron microscopy visualization reveals that the composite fibers exhibit a porous structure consisting of both micropores and mesopores. Electrochemical evaluations of cyclic voltammetry and galvanostatic charge-discharge indicate that the SnO2/C microfibers possess a high capacity and good rate capability compared with commercial SnO2. The improved performances of SnO2/C fibers can be attributed to the nano-size of SnO2 particles dispersed in carbon matrix and the existing nanopores in the SnO2/C microfibers.

show abstract

“…Hydrogel fibers have been made into wound dressings and have demonstrated good physical strength and water absorbency 16 . They also demonstrated good biocompatibility for tissue regeneration purposes 17 .…”

Section: Introductionmentioning

confidence: 99%

The influence of operating parameters on the drug release and antibacterial performances of alginate fibrous dressings prepared by wet spinning

Lin

Wang

2012

Biomatter

View full text Add to dashboard Cite

Wet spinning was used to manufacture fibrous alginate hydrogel wound dressings. Samples manufactured using varied operating parameters (decreased air pressure and calcium concentration or increased nozzle diameter and alginate concentration) were compared with the control samples. The changes in the fiber size, Young’s modulus, swelling ratio, fetal bovine serum (BSA) release efficacy, water vapor transmission rate (WVTR) and bacterial inhibition potential due to alterations of the operating parameters were measured. The samples manufactured using altered operating parameters had larger fiber sizes (p < 0.05) and lower Young’s moduli (p < 0.05). The changes in swelling ratios, BSA release efficacies, WVTR and bacterial inhibition potential showed a significant dependence on the degree of calcium crosslinking of the hydrogel and on how tightly the fibers were bound with one another. By manipulating the operating parameters in the wet-spinning system, wound dressings with different properties were successfully made.

show abstract

Fibres for wound dressings based on mixed carbohydrate polymer fibres

Cited by 64 publications

References 3 publications

Positively and negatively charged ionic modifications to cellulose assessed as cotton-based protease-lowering and hemostatic wound agents

Positively and negatively charged ionic modifications to cellulose assessed as cotton-based protease-lowering and hemostatic wound agents

Synthesis of Nanostructured SnO₂/C Microfibers with Improved Performances as Anode Material for Li-Ion Batteries

The influence of operating parameters on the drug release and antibacterial performances of alginate fibrous dressings prepared by wet spinning

Contact Info

Product

Resources

About

Fibres for wound dressings based on mixed carbohydrate polymer fibres

Cited by 64 publications

References 3 publications

Positively and negatively charged ionic modifications to cellulose assessed as cotton-based protease-lowering and hemostatic wound agents

Positively and negatively charged ionic modifications to cellulose assessed as cotton-based protease-lowering and hemostatic wound agents

Synthesis of Nanostructured SnO2/C Microfibers with Improved Performances as Anode Material for Li-Ion Batteries

The influence of operating parameters on the drug release and antibacterial performances of alginate fibrous dressings prepared by wet spinning

Contact Info

Product

Resources

About

Synthesis of Nanostructured SnO₂/C Microfibers with Improved Performances as Anode Material for Li-Ion Batteries