Fibrillated bacterial cellulose liquid carbene bioadhesives for mimicking and bonding oral cavity surfaces

Singh, Juhi; Steele, Terry W. J.; Lim, Sierin

doi:10.1039/d1tb02044g

Cited by 6 publications

(2 citation statements)

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“…The conjugated protein is made into a film that has 50 μm thickness, is sturdy enough to withstand a weight of 4.5 g, and can maintain the cell metabolism system (6 days) (Raphel et al, 2012). The rapid (60 s) gelation of diazirine led to an oral adhesive application that involved the chemical curing of bromo-diazirine to form carbene of bacterial cellulose (Singh et al, 2021). The rapid gelation (within 60 s) promoted low flowability with up to 35 kPa adhesiveness in wet conditions, which is suitable for mucoadhesive drug delivery (Singh et al, 2021).…”

Section: Benzophenone and Diazirinementioning

confidence: 99%

“…The rapid (60 s) gelation of diazirine led to an oral adhesive application that involved the chemical curing of bromo-diazirine to form carbene of bacterial cellulose (Singh et al, 2021). The rapid gelation (within 60 s) promoted low flowability with up to 35 kPa adhesiveness in wet conditions, which is suitable for mucoadhesive drug delivery (Singh et al, 2021).…”

Section: Benzophenone and Diazirinementioning

confidence: 99%

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Photocrosslinkable natural polymers in tissue engineering

Moon

Hwang²,

Jeon³

et al. 2023

Front. Bioeng. Biotechnol.

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Natural polymers have been widely used in scaffolds for tissue engineering due to their superior biocompatibility, biodegradability, and low cytotoxicity compared to synthetic polymers. Despite these advantages, there remain drawbacks such as unsatisfying mechanical properties or low processability, which hinder natural tissue substitution. Several non-covalent or covalent crosslinking methods induced by chemicals, temperatures, pH, or light sources have been suggested to overcome these limitations. Among them, light-assisted crosslinking has been considered as a promising strategy for fabricating microstructures of scaffolds. This is due to the merits of non-invasiveness, relatively high crosslinking efficiency via light penetration, and easily controllable parameters, including light intensity or exposure time. This review focuses on photo-reactive moieties and their reaction mechanisms, which are widely exploited along with natural polymer and its tissue engineering applications.

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Section: Benzophenone and Diazirinementioning

confidence: 99%

Section: Benzophenone and Diazirinementioning

confidence: 99%

Photocrosslinkable natural polymers in tissue engineering

Moon

Hwang²,

Jeon³

et al. 2023

Front. Bioeng. Biotechnol.

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Novel Functional Dressing Materials for Intraoral Wound Care

Ding,

Zhu,

Zhang

et al. 2024

Adv Healthcare Materials

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Intraoral wounds represent a particularly challenging category of mucosal and hard tissue injuries, characterized by the unique structures, complex environment, and distinctive healing processes within the oral cavity. They have a common occurrence yet frequently inflict significant inconvenience and pain on patients, causing a serious decline in the quality of life. A variety of novel functional dressings specifically designed for the moist and dynamic oral environment have been developed and realized accelerated and improved wound healing. Thoroughly analyzing and summarizing these materials is of paramount importance in enhancing our understanding and proficiently managing intraoral wounds. In this review, the particular processes and unique characteristics of intraoral wound healing are firstly described. Up‐to‐date knowledge of various forms, properties and applications of existing products are then intensively discussed, which are categorized into animal products, plant extracts, natural polymers, and synthetic products. To conclude, this review presents a comprehensive framework of currently available functional intraoral wound dressings, with an aim to provoke inspiration of future studies to design more convenient and versatile materials.This article is protected by copyright. All rights reserved

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