Fibrin glue is a quick and effective treatment for primary and recurrent pilonidal sinus disease

Sian, TS; Herrod, Philip; Blackwell, James; Hardy, Ejo; Lund, Jonathan N.

doi:10.1007/s10151-018-1864-4

Cited by 26 publications

(15 citation statements)

References 32 publications

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“…However, primary midline closure was associated with a recurrence rate up to 67.9% 20 years after surgery [22]. Furthermore, according to our included studies, the recurrence rate after fibrin glue therapy with cleaning the sinus tract ranges from 5.6% to 29% [12][13][14][15][16].…”

Section: Recurrence Of Pilonidal Sinusmentioning

confidence: 99%

A Systematic Review of Fibrin Glue as an Ideal Treatment for the Pilonidal Disease

Win¹,

Went²,

Ruo³

et al. 2021

Cureus

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Pilonidal sinus is an acquired condition caused by irritation to the hair follicles at the natal cleft, presenting with an abscess or chronic infection. It is prevalent in young adults affecting their productive lifestyle with morbidities. There are varieties of treatment options; however, there is no consensus yet for the ideal procedure. Less invasive procedures have evolved to replace the traditional surgical techniques, which cannot significantly reduce the risks of recurrence and wound complications despite extensive surgeries. We aimed to assess the effect of fibrin glue as a primary treatment after cleaning the sinus in pilonidal sinus disease. We searched for articles from PubMed®, Ovid MEDLINE®, Ovid EMBASE®, and Cochrane CENTRAL. Six studies that included 336 patients in total were analyzed. Fibrin glue treatment in these studies reported a quicker return to normal activities postoperatively, a low rate of infection, and an acceptable rate of recurrence. Thus, fibrin glue seems beneficial in the management of pilonidal disease. However, further high-quality studies are essential to support and confirm this evidence. Future research should also evaluate its cost and implications in the ambulatory service.

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Section: Recurrence Of Pilonidal Sinusmentioning

confidence: 99%

A Systematic Review of Fibrin Glue as an Ideal Treatment for the Pilonidal Disease

Win¹,

Went²,

Ruo³

et al. 2021

Cureus

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“…1 2. Minimally invasive procedures that include pit picking, which removes midline pores and cleans out the cyst [7], Gips procedure which is similar to pit picking but uses a skin trephine to remove the midline pores and sinus tract openings [8], SiLaC, which ablates the sinus with laser-generated heat [9], EPSiT, which cleans out the sinus tract under direct endoscopic vision [10], kshar sutra, which ablates the sinus with chemical impregnated thread [11], phenol injection, which chemically cauterizes the sinus tract [12], and fibrin glue, which obliterates the sinus tract [13].…”

Section: Introductionmentioning

confidence: 99%

The Bascom Cleft Lift as a Solution for All Presentations of Pilonidal Disease

Immerman¹

2021

Cureus

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Objective This study is a report on 700 consecutive patients treated with the Bascom cleft lift as treatment for both simple and complex pilonidal diseases between 1993 and 2020. Patients and methods The Bascom cleft lift was used in patients with primary disease, recurrent disease, perianal disease, and failed flap procedures. Some technical modifications had to be made to accommodate patients with perianal disease, and they are described. All patients were treated by the author in private practice clinics and hospitals between 1993 and 2020 and were entered into a database concomitantly with their treatment. Patients were subsequently surveyed in preparation for this study, by phone, email, or email survey to determine the current status. The procedure consisted of excision of the sinus tracts, cysts, and open wounds; raising a skin and subcutaneous tissue flap; and flattening the gluteal cleft. Failure of the procedure was defined as lack of complete healing or recurrent pilonidal disease requiring revisional surgery. Complications were recorded and are described. Results We found that of the 700 patients, 3.4% required revision of the cleft lift (confidence interval for proportion based on binomial distribution: 2.1%-4.8%). The median follow-up time for patients without recurrence was six months (IQR: 2-19.5). Once primary healing was obtained, there were no late recurrences in the 156 patients followed beyond 24 months. Factors that negatively impacted the success rate were having had previous failed pilonidal surgery (5.3% required revision) and open wounds on the edge of the anus (15.5% required revision). Conclusions The Bascom cleft lift had an overall success rate of 96.6%. There was no category of patients for which this was not a good option, but analysis of this data reveals that patients who have had previous failed surgery, and patients with wounds on the edge of the anus had a higher failure rate than the group as a whole.

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“…Cumulative healing after 2 rounds was 96.9%. This procedure does not require technical equipment and can be easily thought and performed [16]. According to Cohran review current evidence is uncertain regarding the benefits associated with fibrin glue as monotherapy in PD or as adjunct to surgery.…”

Section: Minimally-invasive Treatment Of Pdmentioning

confidence: 99%

Pilonidal Disease

Nestorović

Pecić²,

Branković³

et al. 2019

FU Med Biol

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Pilonidal disease is a common and well-recognized medical condition. It affects people in reproductive age, especially men and in combination with in-patient and outpatient treatment and absence from work it causes a considerable socioeconomic loss. This fact led to a renewed interest in understanding of the disease and search for the ideal method of treatment. The purpose of this review was to provide update on therapeutic options for patients with pilonidal disease. In case of chronic or recurrent pilonidal disease various treatment options exist, addressing different measures of surgical outcome. Like for many conditions, there is increase in the use of minimally invasive techniques in the treatment, which could be alternative to surgical excisions for pilonidal disease. Procedures for treatment of pilonidal disease can be divided in two large groups: minimally invasive treatment and excisional procedures. Although various treatment options exist nowadays, surgery is still preferred as definitive treatment. The optimal closure of the wound following an excision is still under debate since outcome measures depend mostly on type of closure selected. Most of the procedures fail to achieve the goals altogether. The final decision on treatment should be made based on surgeon and the patient’ preference.

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Fibrin glue is a quick and effective treatment for primary and recurrent pilonidal sinus disease

Cited by 26 publications

References 32 publications

A Systematic Review of Fibrin Glue as an Ideal Treatment for the Pilonidal Disease

A Systematic Review of Fibrin Glue as an Ideal Treatment for the Pilonidal Disease

The Bascom Cleft Lift as a Solution for All Presentations of Pilonidal Disease

Pilonidal Disease

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