Fibrin monomer could be a useful predictor of pulmonary embolism after total hip arthroplasty: preliminary report

Guidelines for Gastroenterological Endoscopy in Patients Undergoing Antithrombotic Treatment: 2017 Appendix on Anticoagulants Including Direct Oral Anticoagulants

“…Additionally, thrombotic markers including soluble fibrin (SF) or fibrin monomer complex (FMC) can be used to determine the therapeutic effects of anticoagulants and evaluate the risk of thrombus formation (Table ). Soluble fibrin responds more quickly to postoperative deep venous thrombosis than D‐dimer and is a good thrombotic marker for accurately predicting the risk of coronary thrombosis . Furthermore, because its half‐life ranges from 8 h to 11 h, it can be a good marker for assessing the effect of DOAC.…”

Study of Hemostatic Biomarkers in Acute Ischemic Stroke by Clinical Subtype

“…The assay of FMC and SF has recently been shown to be useful for early prognosis or determination of therapeutic efficacy in the development of deep vein thrombosis or postoperative pulmonary embolism. [1][2][3][4] The present study assayed various hemostatic biomarkers over time in patients with acute cerebral infarction to study the usefulness of such markers in assessing the pathology of thrombus formation, subtype diagnosis, and prognosis in the acute stage of cerebral infarction, as well as differences between the various markers.…”

Evaluation of hypercoagulability using soluble fibrin monomer complex in sick newborns

“…25 Measurement of SFMC has been reported to be useful not only for the diagnosis, but also for deciding therapy for patients with DIC, pre-DIC, deep vein thrombosis, pulmonary embolism, and multiple organ failure. [26][27][28][29] Further, the SFMC assay was reported to be a promising method for determining in vivo fibrin formation in patients with acute myocardial infarction, irrespective of whether the primary treatment was fibrinolytic therapy or acute percutaneous coronary angioplasty. 30 Many parameters, such as fibrinopeptide A, prothrombin fragment 1 + 2, TAT, and d-dimer are presently used in the diagnosis of DIC.…”