Fibrinogen Degradation Product-D, Fibrinogen, and Serum Change Polymorphonuclear Granulocyte Activity—Possibly Important Post-trauma?

Patients with stable uncomplicated cirrhosis have normal neutrophil function

“… 19 The MAC1 receptor, which is present on the surface of monocytes and neutrophils, is integral to the proper functioning of these phagocytic cells, facilitating uptake of C3b‐coated particles, mediating adhesive interactions with endothelial cells and extracellular matrix proteins, and binding of complement. 20–24 Recent evidence suggests that fibrinogen degradation products may also modulate neutrophil function, 25–27 perhaps through binding to the MAC1 receptor.…”