Fibro-osseous lesions of the head and neck

Abstract

This review aims to overview key histopathological features and provide diagnostic clues for a selection of the fibro-osseous lesions of the jaws and facial bones. These form a diverse group of conditions with differing aetiologies but similar histological appearances and some may be part of more generalized systemic disease. It will become apparent that for this group of conditions, diagnosis cannot be made by examination of biopsy material by a pathologist in isolation and both clinical and radiological correlation are needed. However, there are some subtle histopathological features that can allow one diagnosis to be favoured over all others which will be outlined here. Identification of these in material sent for histopathological analysis should assist the multidisciplinary team in making a definitive diagnosis.

The 5‐year prevalence of maxillofacial fibro‐osseous lesions in Uganda

“…The most common chief complaint of the patients was swelling at 50.6% followed by swelling with pain at 13.8%. The above findings are in agreement with a number of reports that describe fibrous dysplasia as a painless slow‐growing tumor with episodes of very active growth (Eversole et al , ; Hall, ).…”

An osseous lesion in the maxillary sinus—Tumour or tumour‐like?

“…FD may involve single (monostotic) or multiple (polyostotic) bones (Baumhoer, ; Hall, ; MacDonald‐Jankowski, ). The polyostotic form can be excluded in this case because none of the other skeletal remains exhibited any distinct changes.…”

Craniofacial fibrous dysplasia: A case report and literature review

“…The rate of incidence is more highest in the maxilla that in the mandible. [1,5] Craniofacial FD is restricted to the skull bones and ocular complications, such as visual loss, diplopia, and proptosis, occur in 20%-35% of the cases. [1] Polyostotic FD affects many bones, is relatively rare, and in some cases, is called the Jaffe type.…”

“…The fibroblast show an uniform spindle-shaped nuclei and mitotic figures are not seen. [5,8] FD shows variable radiographic features in relation with the level of maturation, which determines the amount of density. Thus, on plain films, FD may display the following appearances: radiolucent, ground-glass, smoky, cloudy, peau d'orange, finger print, or diffuse sclerosis.…”