Fibromuscular dysplasia of the coronary arteries: a case report and review of the literature

Abstract

Fibromuscular dysplasia is a nonatherosclerotic and non-inflammatory vascular disease with primary lesion of renal and internal carotid arteries. We present a neonatal case of fibromuscular dysplasia who died on the second day of life. The newborn suffered from fibromuscular dysplasia of the coronary arteries and a congenital heart defect. The interesting feature of this case was the formation of aneurysms of the coronary arteries with pulmonary atresia.This case demonstrates a casuistically rare form of association between fibromuscular dysplasia of the coronary arteries and pulmonary artery atresia.

Coronary Artery Aneurysms: A Review of the Epidemiology, Pathophysiology, Diagnosis, and Treatment

“…For the first time, a CAA was reported as a complication of FMD of the intimal, medial, adventitial, and periarterial layers (99). This phenomenon could further the understanding of the underlying mechanisms of congenital CAAs.…”

Fibromuscular Dysplasia of the Coronary Arteries: An Infrequent Cause of Sudden Death

“…In childhood, there are few reported cases. Two of the cases described occurred in newborns, manifesting as cardiogenic shock at birth, both died and the diagnosis was made at autopsy [3,4]. The other two cases occurred in two 12-year-old adolescents, one of them presented SCD, diagnosed after autopsy [5] and the other presented AMI, surviving after performing percutaneous transluminal coronary angioplasty [6].…”

2 Cases of Spontaneous Coronary Artery Dissection in Neonates

“… 6 A 2-day-old infant with tetralogy of Fallot was found to have coronary artery FMD, with the classic “string of beads” appearance, but without histologic confirmation. 7 …”