Fibromyalgia and Chronic Fatigue Syndrome in the Age of COVID-19

Mohabbat, Arya B.; Mohabbat, Nikita Maria L.; Wight, Elizabeth

doi:10.1016/j.mayocpiqo.2020.08.002

Cited by 54 publications

(63 citation statements)

References 4 publications

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“…Fibromyalgia (FM) is a chronic centralized pain sensitivity disorder with widespread, wandering, increasing-decreasing pain attacks accompanied by fatigue, sleep disturbance, mood disorders, and somatic symptoms [ 8 ]. In controlled studies in the literature, psychological, physical and/or autoimmune stressors were found to increase FM symptoms [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

The effects of COVID-19 fear and anxiety on symptom severity, sleep quality, and mood in patients with fibromyalgia: a pilot study

et al. 2021

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Background During the COVID-19 pandemic, individuals faced psychological stress caused by fear and anxiety due to the high transmission and mortality rate of the disease, the social isolation, economic problems, and difficulties in reaching health services. Fibromyalgia (FM) is a chronic centralized pain sensitivity disorder. Psychological, physical and/or autoimmune stressors were found to increase FM symptoms. This pilot study aimed to evaluate the COVID-19 fear and anxiety level, and to examine their effect on disease severity, sleep quality, and mood in FM patients compared to control group. Methods This pilot study conducted as a cross-sectional study, and included 62 participants. Participants were divided into two groups: FM patient group (n = 31) and control group (n = 31). Symptom severity, sleep quality, and mood were determined using the Revised Fibromyalgia Impact Questionnaire (FIQR), Pitsburg Sleep Quality Index (PSQI), and Hospital Anxiety Depression Scale (HADS), respectively. In order to evaluate the level of COVID-19 fear and anxiety, the Fear of COVID-19 Scale (FCV-19S) and Coronavirus Anxiety Scale (CAS) were used compared to control group. Results FIQR, PSQI, HAD-A, HAD-D, FCV-19S and CAS scores were significantly higher in the FM group (p = 0.01). A positive significant correlation was found between FCV-19S and CAS results and FIQR, PSQI, and HAD-anx results in FM patients (p < 0.05). Conclusion This pilot study showed that, the individuals with FM can be more affected by psychological stress, and this situation negatively affects the symptom severity, sleep quality, and mood in FM patients, so these patients should be closely monitored in terms of psychological stressors and their effects during pandemics. More studies with more participants are necessary to describe the challenges lived by fibromyalgia population.

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Section: Introductionmentioning

confidence: 99%

The effects of COVID-19 fear and anxiety on symptom severity, sleep quality, and mood in patients with fibromyalgia: a pilot study

et al. 2021

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“…About 40-60% survey takers were familiar that viral infections can cause skin warts, Liver Cirrhosis, and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS; an unexplained, chronic disease that affects millions worldwide [22,23]) (Fig 6A). Of note, there is an emerging body of evidence indicating that a section of the COVID-19 patients, especially the long haulers, will eventually develop ME/CFS [24,25]. To nd whether the survey takers had other underlying health conditions that might exacerbate the effects of COVID-19, we shortlisted a few disorders that are believed to have that effect.…”

Section: Resultsmentioning

confidence: 99%

Global Survey-based Assessment of Lifestyle Changes During the COVID-19 Pandemic

Agarwal

Kaushik

Sarkar

et al. 2021

Preprint

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Along with the major impact on public health, the COVID-19 outbreak has caused unprecedented concerns ranging from sudden loss of employment to mental stress and anxiety. We implemented a survey-based data collection platform to characterize how the COVID-19 pandemic has affected the socio-economic, physical and mental health conditions of individuals. We focused on three broad areas, namely, changes in social interaction during home confinement, economic impact and their health status. We identified a substantial increase in virtual interaction among individuals, which might be a way to alleviate the sudden unprecedented mental health burden, exacerbated by general awareness about viral infections or other manifestations associated with them. The majority of participants (85%) lived with one or more companions and unemployment issues did not affect 91% of the total survey takers, which was one of the crucial consequences of the pandemic. Nevertheless, measures such as an increased frequency of technology-aided distant social interaction, focus on physical fitness and leisure activities were adopted as coping mechanisms during this period of home isolation. Collectively, these metrics provide a succinct and informative summary of the socio-economic and health impact of the COVID-19 pandemic on the individuals. Findings from our study reflect that continuous surveillance of the psychological consequences for outbreaks should become routine as part of preparedness efforts worldwide. Given the limitations of analyzing the large number of variables, we have made the raw data publicly available on the OMF ME/CFS Data Center server to facilitate further analyses. (Public URL will be added after acceptance).

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“…The exact mechanism of myalgia post-viral infection is unknown. Central sensitization and hyper-responsivity to pain have been identified as the primary pathophysiological etiologies of myalgia and CFS [35,36]. Some studies have discussed whether SARS-CoV-2 can affect skeletal muscle cells by binding with ACE2 alone or with other pro-inflammatory cytokines, resulting in cell damage and expression of growth factors, with excessive stimulation of the dorsal root ganglia [37].…”

Section: Myalgiamentioning

confidence: 99%

“…SARS-CoV-2 intensifies catabolism, resulting in protein degradation and low muscle development and regeneration [35,38]. Short-and long-term musculoskeletal complications are anticipated in patients recovering from moderate to severe COVID-19 symptoms.…”

Section: Myalgiamentioning

confidence: 99%

Health Complications in Patients Recovering from COVID-19: A Narrative Review of Post-COVID Syndrome

Pai

Park

Chen

et al. 2021

JAMMR

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Introduction: Due to the unprecedented health and economic complications resulting from COVID-19, the coronavirus pandemic is currently a leading global health concern. COVID-19 poses significant health risks, life-threatening clinical conditions, and even mortality in affected individuals. Several associated complications have also arisen as a result of COVID-19, including mass hospitalization, the need for invasive ventilation and intensive care unit (ICU) support, delayed recovery from infection, and post-recovery health issues. Furthermore, the pandemic itself has created enormous panic, which in turn affects the mental health of COVID-19 patients, individuals who have recovered from the disease, and the general population. Just over a year has now passed since the beginning of the global COVID-19 pandemic and in this time, over 110 million individuals have been infected worldwide. Post-infection recovery times and long-term complications are now becoming more apparent. Especially physical and mental health complications arising from post-COVID-19-infection, which prevent a return to a healthy lifestyle and everyday routine remain a critical issue. Objective: The primary objective of this narrative review is to address this clinically relevant issue and overview the health complications commonly observed in individuals who have recovered from COVID-19. Methods: An investigation was performed on online databases for relevant articles from 2020 until January 2021. Key index words used in search were post-covid, myalgia, fatigue, pain. Results: Fatigue, myalgia (i.e., muscle pain), sleep disruptions, and mental health issues (e.g., anxiety and depression) are among the most reported post-recovery symptoms in patients recovering from the disease. The etiology and potential management of these health complications are discussed, considering recently published findings from COVID-19 patients as well as previous studies focusing on complications arising from other related pandemics. Conclusion: Patients who have recovered from COVID-19 should be evaluated for signs of fatigue, muscle pain, mental health difficulties, and sleeping difficulties regardless of disease severity. Based on this review of the literature, complete clinical and psychiatric evaluation, and the use of validated indicators of the severity of COVID-19 disease, symptoms are recommended to develop efficient health management approaches that meet patients' needs.

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Fibromyalgia and Chronic Fatigue Syndrome in the Age of COVID-19

Cited by 54 publications

References 4 publications

The effects of COVID-19 fear and anxiety on symptom severity, sleep quality, and mood in patients with fibromyalgia: a pilot study

The effects of COVID-19 fear and anxiety on symptom severity, sleep quality, and mood in patients with fibromyalgia: a pilot study

Global Survey-based Assessment of Lifestyle Changes During the COVID-19 Pandemic

Health Complications in Patients Recovering from COVID-19: A Narrative Review of Post-COVID Syndrome

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