2013
DOI: 10.1503/cmaj.121414
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Fibromyalgia: evolving concepts over the past 2 decades

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Cited by 31 publications
(27 citation statements)
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“…In the majority of CFS patients, this chronic fatigue is accompanied by widespread and persistent pain as well (1). Chronic widespread musculoskeletal pain is the hallmark symptom of fibromyalgia (FM), and furthermore it is known that patients with CFS and patients with FM share many other symptoms and clinical features such as fatigue, sleep disturbances, cognitive dysfunction, and mood disturbances (2)(3)(4)(5). A growing body of scientific literature designates central sensitisation (CS) as a common pathophysiological mechanism in these overlapping conditions (6)(7)(8)(9).…”
Section: Participants and Assessmentsmentioning
confidence: 99%
“…In the majority of CFS patients, this chronic fatigue is accompanied by widespread and persistent pain as well (1). Chronic widespread musculoskeletal pain is the hallmark symptom of fibromyalgia (FM), and furthermore it is known that patients with CFS and patients with FM share many other symptoms and clinical features such as fatigue, sleep disturbances, cognitive dysfunction, and mood disturbances (2)(3)(4)(5). A growing body of scientific literature designates central sensitisation (CS) as a common pathophysiological mechanism in these overlapping conditions (6)(7)(8)(9).…”
Section: Participants and Assessmentsmentioning
confidence: 99%
“…1 I support many of the recommendations in the 2012 Canadian guidelines, 2 including the need to increase the capacity of primary care physicians to make an accurate diagnosis and initiate management of fibromyalgia, referring patients to specialists only if further expertise is required. I also agree that patients should be encouraged to take an active role in their own management and to engage in multimodal treatment.…”
Section: Concerns With Fibromyalgia Guidelinesmentioning
confidence: 88%
“…3 I would like to highlight 3 concerns with the new Canadian guidelines 2 and their summary in CMAJ. 1 First, the article 1 does not clearly state that although fibromyalgia and major depression can be comorbid, they are not the same condition and they do not respond to the same treatments. The authors show that selective serotonin reuptake inhibitors are ineffective in fibromyalgia.…”
Section: Concerns With Fibromyalgia Guidelinesmentioning
confidence: 99%
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“…Hypersensitivity of central nervous system neurons, malfunction of pain pathways, and atypical hormone responses have been proposed as probable causes for the amplified pain experience (Abeles, Pillinger, Solitar, & Abeles, 2007). Despite these scientific advances, the validity of FMS has remained a source of debate among healthcare providers (HCPs) (Fitzcharles, Ste-Marie, & Pereira, 2013;Grob, 2011;Wolfe, 2009). …”
Section: Introductionmentioning
confidence: 99%