Fibromyalgia is associated to receiving chronic medications beyond appropriateness: a cross-sectional study

Rivera, Javier; Vallejo, M.

doi:10.1007/s00296-016-3568-2

Cited by 9 publications

(2 citation statements)

References 28 publications

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“…A study from Spain, based on a telephone interview, found a usage rate of 16% for NSAIDs and 7.5% for opiates [ 43 ]. Studies based on actual purchases reported usage rates of 56–68% for NSAIDs and 14–56% for opiates [ 44 – 48 ]. Our findings show a higher rate of opiate use among FM patients in southern Israel than in the rest of the country [ 48 ] and one of the highest rates reported in the literature.…”

Section: Discussionmentioning

confidence: 99%

Medication use and factors associated with opiate use among patients with diagnosed fibromyalgia from two ethnic sectors in southern Israel

Treister-Goltzman

Peleg

Sagy

et al. 2023

J of Pharm Policy and Pract

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Background Our aims were to compare fibromyalgia (FM) rate, drug treatment and factors associated with the use of opiates in two ethnic sectors. Methods A retrospective cross-sectional study in southern district of Israel was performed on diagnosed FM patients in 2019–2020 [7686 members (1.50%)]. Descriptive analyses were conducted and multivariable models for the use of opiates were developed. Results There were significant differences between the two ethnic groups in FM prevalence at 1.63% and 0.91% in the Jewish and Arab groups, respectively. Only 32% of the patients used recommended medications and about 44% purchased opiates. Age, BMI, psychiatric co-morbidity, and treatment with a recommended drug were similarly associated with an increased risk for opiate use in both ethnic groups. However, male gender was associated with × 2 times reduced risk to use opiates only among the Bedouins (aOR = 0.552, 95%CI = 0.333–0.911). In addition, while in both of ethnic groups the existence of another localized pain syndrome was associated with an increased risk for opiates use, this risk was 4 times higher in the Bedouin group (aOR = 8.500, 95%CI = 2.023–59.293 and aOR = 2.079, 95%CI = 1.556–2.814). Conclusions The study showed underdiagnosis of FM in the minority Arab ethnicity. Female Arab FM patients in low or high, compared to middle socio-economic status, were a risk group for excess opiate use. Increased use of opiates and very low rate of purchase of recommended drugs point to a lack of effectiveness of these drugs. Future research should assess whether the treatment of treatable factors can reduce the dangerous use of opiates.

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Section: Discussionmentioning

confidence: 99%

Medication use and factors associated with opiate use among patients with diagnosed fibromyalgia from two ethnic sectors in southern Israel

Treister-Goltzman

Peleg

Sagy

et al. 2023

J of Pharm Policy and Pract

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“…They act at different levels. The main symptoms of the disease are generally treated with a pharmacological approach (Macfarlane et al, 2016), combined with a close monitoring of the eventual overuse or chronic use of drugs (Rivera & Vallejo, 2016). Another important step of the care is to provide education about the disease, the realistic goals that can be set during the treatment, the activities that have to be gradually introduced, the management of sleep and the communication with the others (Turk & Adams, 2016).…”

Section: Implications For the Treatmentmentioning

confidence: 99%

Toward a Transdisciplinary Integration of the Health Disciplines: The Case of the Fibromyalgia Syndrome

Giusti

2017

Journal for Perspectives of Economic Political and Social Integration

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Fibromyalgia is a chronic pain disorder with a multifaceted nature and its biological, psychological and social aspects are strongly interconnected. Therefore, the integration of the different health disciplines is strongly recommended for its care. There is a growing number of interventions based on this principle but each of them is heterogeneous with regards to how the included disciplines are integrated with each other. With this regards, multidisciplinary and interdisciplinary programs are distinguished. The former are organized in order to treat the various aspects of the syndrome using different perspectives and their various treatment components are usually provided separately by the different care providers. Conversely, interdisciplinary treatments are planned in order to foster a dialogue between the operators by providing a joint conduction of the treatment or scheduling plenary discussions about the cases. In the field of chronic pain, some authors are suggesting to move beyond these approaches and to plan transdisciplinary treatments, which would allow the professionals to move across their disciplinary boundaries. Although no examples of these interventions have been proposed for the treatment of fibromyalgia, there is a visible trend in the literature toward more holistic forms of care.

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Pharmacological Treatment of Fibromyalgia Syndrome: A Practice-Based Review

Giorgi,

Sarzi-Puttini,

Pellegrino

et al. 2024

Curr Pain Headache Rep

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Purpose of Review Fibromyalgia Syndrome (FMS) is a complex chronic pain condition characterized by widespread musculoskeletal pain and numerous other debilitating symptoms. The purpose of this review is to provide a comprehensive overview, based on everyday clinical practice, of the drugs presently employed in the treatment of FMS. Recent Findings The treatment of FMS is based on a multimodal approach, with pharmacologic treatment being an essential pillar. The drugs used include tricyclic antidepressants, serotonin and noradrenaline reuptake inhibitors, other antidepressants, anticonvulsants, myorelaxants, and analgesics. The effectiveness of these medications varies, and the choice of drug often depends on the specific symptoms presented by the patient. Many drugs tend to either address only some domains of the complex FMS symptomatology or have a limited effect on pain. Summary Each treatment option comes with potential side effects and risks that necessitate careful consideration. It may be beneficial to divide patients into clinical subpopulations, such as FMS with comorbid depression, for more effective treatment. Despite the complexities and challenges, the pharmacological treatment remains a crucial part for the management of FMS. This review aims to guide clinicians in prescribing pharmacological treatment to individuals with FMS.

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Fibromyalgia is associated to receiving chronic medications beyond appropriateness: a cross-sectional study

Cited by 9 publications

References 28 publications

Medication use and factors associated with opiate use among patients with diagnosed fibromyalgia from two ethnic sectors in southern Israel

Medication use and factors associated with opiate use among patients with diagnosed fibromyalgia from two ethnic sectors in southern Israel

Toward a Transdisciplinary Integration of the Health Disciplines: The Case of the Fibromyalgia Syndrome

Pharmacological Treatment of Fibromyalgia Syndrome: A Practice-Based Review

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