Fibromyalgia syndrome in Turkish hemodialysis patients

Abstract

The aim of our study was to evaluate the frequency of fibromyalgia syndrome (FMS) in hemodialysis (HD) patients and to assess whether this syndrome is associated with gender, age, duration of HD, or various laboratory parameters. This study was composed of 221 chronic HD patients (99 females and 122 males), and we recorded each participant's age, gender, causes of kidney failure, HD duration, education level, and symptoms related to FMS, which was diagnosed according to the 2010 American College of Rheumatology criteria. We documented the laboratory parameters for all patients. In addition, patients with FMS filled out the Fibromyalgia Impact Questionnaire. Twenty-two patients met the diagnostic criteria for FMS (9%), and there were no statistically significant differences related to age, gender, or HD duration between FMS and non-FMS groups (P > 0.05). In addition, the education levels were lower in patients diagnosed with FMS (P < 0.05), and there were statistically significant differences related to sleep disturbance, fatigue, and cognitive symptoms between the two groups (P < 0.05) as well. However, their laboratory parameters were similar (P > 0.05). There was a higher prevalence of FMS in HD patients than in the general population. Sleep disturbances, fatigue, education level, and cognitive symptoms were associated with FMS, but there was no correlation between the laboratory parameters and this condition.

Hemodiyaliz Hastalarında Fibromiyalji Sendromu Prevalansı ve Yaşam Kalitesine Etkisi

“…6,16 Nevertheless, in earlier studies of the prevalence of FM in hemodialysis patients, no statistically significant correlation was found between age and FM. 12,15 O u r findings are in keeping with this.…”

“…7 While previous studies [12][13][14] of hemodialysis patients have reported a female preponderance, Leblebici et al did not find any relationship between gender and FM in their study on hemodialysis patients. 15 In our study, 100% of the 33 patients with a diagnosis of FM were women. FM was not observed in male patients, which is in contrast to the findings reported by Wolfe et al where 0.5% of cases of FM in the general population were identified in males.…”

“…3). 15 In the USA, Wolfe et al investigating 3006 individuals from the general population found the FM prevalence to be 2%; 3.4% in females, and 0.5% in males. 16 In the present cohort the FM frequency was 13.3%, higher than the normal population.…”

Periton Diyalizi ve Hemodiyaliz Uygulanan Hastalarda Fibromiyalji Sendromu

“…21 In a study from Turkey, higher prevalence (9%) in hemodialysis patients and statistically signifi cant differences in cognitive symptoms between fi bromyalgia and nonfi bromyalgia groups was reported. 20 In another study, the prevalence was reported as 7,4% with female predominant of 122 hemodialysis patients and it was reported similar rates compared with the control group. 21 Also, depression was correlated with fi bromyalgia.…”

“…19 Higher serum levels of PTH and calcium were associated with chronic pain in patients with hemodialysis. 20 Fibromyalgia is one of the reasons that cause chronic widespread pain in CKD. Also, higher serum PTH levels may cause similar symptoms with FMS.…”