Fibrosarcoma at the site of a metallic fixation of the tibia--a case report and literature review

Hinarejos, Pedro; Escuder, Maria C; Monllau, Juan Carlos; Álvarez, Pedro; Lloreta, J.; Ballester, J

doi:10.1080/000164700317412004

Cited by 7 publications

(2 citation statements)

References 32 publications

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“…Two cases of fibrosarcoma are related to the high grade category, being very cellular with marked cytologic atypia, brisk mitotic activity, and evident necrosis, whereas the other case is of a low grade with morphologic resemblance to the normal fibroblasts. Reticulin fibers were observed clearly surrounding individual cells at their poles, as was described by others (11,14,36,37) .…”

Section: Discussionsupporting

confidence: 82%

Soft tissue sarcomas in Mosul: a pathologic evaluation

Lazim¹,

Al-Irhayim²

2008

Ann Coll Med Mosul

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Objective: Histochemical and immunohistochemical examination of soft tissue sarcomas(STS) in Mosul to assess the value of these techniques in verifying the primary diagnosis. Methods: Paraffin embedded tissue blocks of 35 cases of soft tissue sarcomas collected over a period of 20 months in Mosul, were utilized. H&E, reticulin ,and Van Gieson's staining techniques and immunohistochemical marker for S-100 protein were applied to all the cases. Results: Soft tissue sarcoma accounts for 16.4%of the total of 213 cases of benign and malignant soft tissue neoplasms,with a mean age of 30.5 years ,and a male preponderance(Male: Female ratio of1.7:1). The most common histologic subtypes are extraskeletal Ewing's sarcoma(ES), dermatofibrosarcoma protuberans(DFSP) ,and spindle cell sarcoma, not other wise specified (NOS). The extremities are affected in 51.4% of all cases, particularly the lower limbs. The majority of soft tissue sarcomas belong to the high grade category by applying French Federation of Cancers Centers Sarcoma Group (FFCCSG) and American Joint Cancer Committee (AJCC) grading schemes .Both reticulin and Van Gieson's stains have been successfully depicting the growth patterns of different subtypes. Immunoreactivity for S-100 protein was positive in two cases. Conclusions: High quality H&E stained sections remain the best method for establishing the diagnosis of sarcomas .Reticulin stain proved extremely helpful in subclassifying sarcomas and S-100 protein was instrumental in changing the diagnosis of sarcoma in one case.

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Section: Discussionsupporting

confidence: 82%

Soft tissue sarcomas in Mosul: a pathologic evaluation

Lazim¹,

Al-Irhayim²

2008

Ann Coll Med Mosul

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“…31 Additionally, there are several case reports of rare connective tissue neoplasms such as angiosarcoma, fibrosarcoma, and osteosarcoma arising adjacent to stainless steel plates. [32][33][34] While titanium is widely viewed as more biocompatible than stainless steel, with less corrosion, titanium particles have some inhibitory effects on osteoblast cytoskeletal function, impairing adhesion, proliferation, and viability, however less so than stainless steel. 35,36 Although biopolymers do not exhibit as many problems with biocompatibility as metals, they have been shown to lead to reactions such as osteolysis, synovitis, and sterile sinus tract and abscess formation.…”

Section: Applications Of Biomaterials To Plate and Screw Fixationmentioning

confidence: 99%