FibroScan predicts ascites after liver resection for hepatitis B virus-related hepatocellular carcinoma: A prospective cohort study

Abstract

FibroScan value was a reliable surrogate marker for predicting postoperative ascites should be routinely performed in patients with HBV-related HCC undergoing liver resection.

2022 KLCA-NCC Korea practice guidelines for the management of hepatocellular carcinoma

“…[271][272][273][274] The optimal LSM cut-off value varies according to background liver condition and measurement methods. 271,[274][275][276][277] Recently, a meta-analysis study and the EASL guidelines reported that significant risk of posthepatectomy liver failure can be predicted by liver stiffness above 11.3-14.2 kPa and 12-14 kPa, respectively. 278 Dynamic contrast-enhanced CT is the basic test utilized as a preoperative radiologic study to assess the possibility of resection.…”

2022 KLCA-NCC Korea practice guidelines for the management of hepatocellular carcinoma

“…[271][272][273][274] The optimal LSM cut-off value varies according to background liver condition and measurement methods. 271,[274][275][276][277] Recently, a meta-analysis study and the EASL guidelines reported that significant risk of posthepatectomy liver failure can be predicted by liver stiffness above 11.3-14.2 kPa and 12-14 kPa, respectively. 278 Dynamic contrast-enhanced CT is the basic test utilized as a preoperative radiologic study to assess the possibility of resection.…”

Good performance of liver stiffness measurement in the prediction of postoperative hepatic decompensation in patients with cirrhosis complicated with hepatocellular carcinoma

“…Although there are 8 studies that have validated the use of LSM in the prediction of PHLF [11][12][13][14][15][16][17][18], only one compared LSM with the direct intraoperative measurement of the portal pressure [18]. The direct comparison between LSM and HVPG in this clinical scenario was performed in 97 patients and confirmed the good ability of LSM to identify patients with CSPH, but in this report the patients with CSPH were excluded from hepatic resection [19].…”

“…Recently its role in risk assessment was endorsed by the Baveno VI recommendation [3] and LS values of more than 21 kPa are able to rule-in CSPH. The performance of LSM in the prediction of PHLF were good in the previous studies [11][12][13][14][15][16][17][18], with AUROCs ranging from 0.79 [13] to 0.86 [12], but none of the studies compared LSM with HVPG and the great majority used end-points based on the "50-50 criteria". The only study that used invasive measurement of portal pressure (intraoperatory measurement by direct puncture of the portal vein) and 3-months decompensation as end-point, found that LSM is slightly better than portal pressure measurement in prognosis assessment, with an AUROC of 0.81 for LSM vs 0.71 for direct portal pressure measurement [18].…”