Fibrous cartilage of human menisci is less shock-absorbing and energy-dissipating than hyaline cartilage

Gaugler, Mario; Wirz, Dieter; Ronken, Sarah; Hafner, Mirjam; Göpfert, Beat; Friederich, Niklaus F.; Elke, R.

doi:10.1007/s00167-014-2926-4

Cited by 25 publications

(23 citation statements)

References 17 publications

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“…Low fibrillar stiffness, high permeability, and reasonably high nonfibrillar matrix modulus help tissue deformations and dissipation under prolonged loading conditions. It may be that the meniscus, which was not considered here, may be the elastic shock absorber in the knee while the tibial plateau cartilage contributes primarily to the viscous dissipation of loads (Danso et al, 2015;Gaugler et al, 2014;Pereira et al, 2014).…”

Section: Discussionmentioning

confidence: 97%

Very early osteoarthritis changes sensitively fluid flow properties of articular cartilage

Mäkelä

Han

Herzog

et al. 2015

Journal of Biomechanics

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In this study, fibril-reinforced poroelastic (FRPE) modeling was used for rabbit knee after anterior cruciate ligament transection (ACLT) to assess how the mechanical properties of collagen, proteoglycans, and fluid in articular cartilage change in early osteoarthritis, and how site-specific these changes are. Unilateral ACLT was performed in eight skeletally mature, female New Zealand white rabbits. A separate control (CTRL) group consisted of knee joints of five non-operated rabbits. Animals were sacrificed at four weeks after ACLT and cartilage-on-bone samples from femoral groove, medial and lateral femoral condyles, and tibial plateaus were harvested. A stress-relaxation protocol in indentation geometry was applied and the FRPE model was fitted to the experimental force-time curve by minimizing the mean absolute error between experiment and simulation. The optimized parameters were: fibril network modulus (Ef), representing the collagen network; non-fibrillar matrix modulus (Enf), representing the PG matrix; and permeability (k), representing fluid flow. Permeability was increased significantly in the ACLT group compared to the CTRL group knees at all sites except for the medial tibial plateau. ACLT also caused a decrease in the Ef at all sites except for the medial and lateral tibial plateaus. The Enf of the ACLT group knees was altered only for the lateral femoral condyle. The results of this study suggest that early osteoarthritis primarily affects cartilage permeability and impairs the collagen network stiffness in a site-specific manner. These findings from early osteoarthritis indicate that fluid flow velocity in articular cartilage may change prior to quantifiable structural alterations in the tissue.

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Section: Discussionmentioning

confidence: 97%

Very early osteoarthritis changes sensitively fluid flow properties of articular cartilage

Mäkelä

Han

Herzog

et al. 2015

Journal of Biomechanics

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“…For example, it has been shown that hyaline cartilage serves as a better shock absorber than fibrous menisci. 28 This finding suggests that a loss of cartilage may induce a reduced shock absorption capacity of the joint, increasing loads on the subchondral bone. Moreover, anterior cruciate ligament (ACL) lesions have been shown to alter knee kinematics.…”

mentioning

confidence: 99%

The Influence of Joint Loading on Bone Marrow Lesions in the Knee

et al. 2015

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“…In 2009, Bursac et al showed that collagen content, proteoglycan content, and tensile properties of menisci from donors younger than 45 years old were not agedependent [21]. Shock absorption properties of fibrous cartilage in the meniscus were later studied in 2015 [22]. The authors observed that the dynamic modulus of elasticity in hyaline cartilage was approximately ten times higher than that in the meniscus, while the loss angle in fast indentation stayed at the range of hyaline cartilage.…”

Section: Collagen Fiber Viscoelasticity and Shock Absorptionmentioning

confidence: 99%

Evolution of knowledge on meniscal biomechanics: a 40 year perspective

Mohamadi

Momenzadeh

Masoudi

et al. 2021

BMC Musculoskelet Disord

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Background Knowledge regarding the biomechanics of the meniscus has grown exponentially throughout the last four decades. Numerous studies have helped develop this knowledge, but these studies have varied widely in their approach to analyzing the meniscus. As one of the subcategories of mechanical phenomena Medical Subject Headings (MeSH) terms, mechanical stress was introduced in 1973. This study aims to provide an up-to-date chronological overview and highlights the evolutionary comprehension and understanding of meniscus biomechanics over the past forty years. Methods A literature review was conducted in April 2021 through PubMed. As a result, fifty-seven papers were chosen for this narrative review and divided into categories; Cadaveric, Finite element (FE) modeling, and Kinematic studies. Results Investigations in the 1970s and 1980s focused primarily on cadaveric biomechanics. These studies have generated the fundamental knowledge basis for the emergence of FE model studies in the 1990s. As FE model studies started to show comparable results to the gold standard cadaveric models in the 2000s, the need for understanding changes in tissue stress during various movements triggered the start of cadaveric and FE model studies on kinematics. Conclusion This study focuses on a chronological examination of studies on meniscus biomechanics in order to introduce concepts, theories, methods, and developments achieved over the past 40 years and also to identify the likely direction for future research. The biomechanics of intact meniscus and various types of meniscal tears has been broadly studied. Nevertheless, the biomechanics of meniscal tears, meniscectomy, or repairs in the knee with other concurrent problems such as torn cruciate ligaments or genu-valgum or genu-varum have not been extensively studied.

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Fibrous cartilage of human menisci is less shock-absorbing and energy-dissipating than hyaline cartilage

Cited by 25 publications

References 17 publications

Very early osteoarthritis changes sensitively fluid flow properties of articular cartilage

Very early osteoarthritis changes sensitively fluid flow properties of articular cartilage

The Influence of Joint Loading on Bone Marrow Lesions in the Knee

Evolution of knowledge on meniscal biomechanics: a 40 year perspective

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