Fibrous Dysplasia of Mandible: A Case Report

Abstract

Craniofacial fibrous dysplasia is one of the three types of fibrous dysplasia that can affect the bones of the craniofacial complex, including the mandible and maxilla. Fibrous dysplasia is a non-neoplastic hamartomatous developmental fibro-osseous lesion of the bone-forming mesenchyme that manifests as a defect in osteoblastic differentiation and maturation. It is a lesion of unknown aetiology, uncertain pathogenesis, and diverse histopathology. Fibrous dysplasia represents about 5% of all bone tumours and over 7% of all benign tumours of body. Monostotic fibrous dysplasia of the mandible is an unusual manifestation of the disease that is usually benign, occurs in young individuals, and is managed by conservative curettage or debridement. We present a rare case of unilateral fibrous dysplasia of left side of mandible. The clinical diagnostic approach including imaging studies: Orthopantomogram (OPG) and 3D tomography is described. Histological examination served an adjunctive role; however, the final diagnosis was obtained after excision of the swelling and confirming it by histopathological examination and it was diagnosed as benign fibrous dysplasia.