Fibrous hamartoma of infancy

Scott, Diane; Peña, José Ramón Alonso; Omura, Emily F.

doi:10.1016/s0190-9622(99)70345-2

Cited by 36 publications

(22 citation statements)

References 9 publications

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“…The tumor occurs predominantly on the trunk, especially the axilla and upper extremities, but it has also been reported infrequently on the distal extremities, head, neck, and scrotum [4][5][6]. Multiple coarse hairs on the surface of the mass have been reported, as seen in our case [7]. Efem and Ekpo reported six cases of untreated FHI in which the lesions enlarged rapidly up to the age of 5 years, when growth slowed down but did not stop, nor did the lesions regress [8].…”

Section: Discussionsupporting

confidence: 60%

A case of recurrent and synchronous fibrous hamartoma of infancy

et al. 2005

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We retrospectively reviewed the chart of a patient with recurrent fibrous hamartoma of infancy (FHI). This lesion presented as a gradually enlarging mass on the child's buttock. The child, a 6-month-old male, was followed up, and at 19 months of age the mass was excised. Eighteen months after the initial operation, a local recurrence was noticed. Forty-one months after the initial operation, reexcision was performed. Both masses demonstrated the characteristic features of FHI, which should be considered in the differential diagnosis of subcutaneous mass in young children.

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Section: Discussionsupporting

confidence: 60%

A case of recurrent and synchronous fibrous hamartoma of infancy

et al. 2005

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“…[2] Ultrastructural studies have demonstrated the composition of FHI to include fibroblasts, myofibroblasts, primitive mesenchymal cells, small blood vessels, and mature adipocytes. [48] Immunohistochemical studies of FHI support the ultrastructural findings. [49]…”

Section: Discussionmentioning

confidence: 74%

Fibrous hamartoma of infancy

Vinayak

Kumar

Chandana

et al. 2011

Indian Dermatol Online J

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Fibrous hamartoma of infancy (FHI) is a rare, benign tumor of the subcutis and lower dermis, which usually occurs within the first 2 years of life. Ninety one percent of the tumors occur in the first year of life. The histogenesis of FHI is unclear. The clinical course is typically benign and prognosis excellent. The physical characteristics of the subcutaneous mass in a child may suggest a malignant process; however, FHI should be included in the differential diagnosis. The prognosis of FHI is excellent with local surgical excision and it rarely recurs.

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“…1,4,9,10 A published clinical photograph of one case showed multiple coarse hair over the surface of the lesion, which had been previously unreported. 11 Ultrasonography reveals a mixed echogenicity that may be suggestive of hemangioma, lymphangioma, or lipoma. Generally no other radiologic investigations are recommended.…”

Section: Discussionmentioning

confidence: 99%